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The Novel Pathogenic Mutation c.849dupT in BRCA2 Contributes to the Nonsense-Mediated mRNA Decay of BRCA2 in Familial Breast Cancer

Li S, Ma J, Hu C, Zhang X, Xiao D, Hao L, Xia W, Yang J, Hu L, Liu X, Dong M, Ma D, Liu R

In this study, we used next-generation sequencing methods to screen 300 individuals for BRCA1 and BRCA2. A novel mutation (c.849dupT) in BRCA2 was identified in a female patient and her...
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Analysis of KTDB Registered Trauma Patients from a Single Trauma Center in Korea

Yu B, Chung M, Lee G, Lee M, Park J, Choi K, Hyun S, Jeon Y, Ma D, Yoon YC, Lee J

PURPOSE: Establishment of the trauma system changed quality of trauma care in many countries. As one of the first designated level 1 trauma center in Korea, we analyzed trauma registration...
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Anesthetics or anesthetic techniques and cancer surgical outcomes: a possible link

Alam A, Rampes S, Patel S, Hana Z, Ma D

As of 2018 cancer is responsible for almost 9.6 million deaths annually and, with an aging population, the incidence of cancer is expected to continue to rise. Surgery is an...
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Development and validation of risk score for predicting spontaneous rupture of hepatocellular carcinoma

Ye F, Ma D, Gong XY, Yang YC, Chen YJ

Purpose: Spontaneous rupture is a potentially serious complication of liver cancer. A risk score was developed and validated for predicting spontaneous rupture based on a retrospective study. Methods: Multiple logistic regression...
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Prefabrication of Axially Vascularized Bone by Combining β-Tricalciumphosphate, Arteriovenous Loop, and Cell Sheet Technique

Ma D, Ren L, Cao Z, Li J, Cao J, Tian W, Yao H

The repair of bone defects poses a great challenge for reconstructive surgeons. Although the development of tissue engineering has exhibited promise in replacing damaged bone, the fabrication of large constructs...
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Antinociceptive effects of oleuropein in experimental models of neuropathic pain in male rats

Chen H, Ma D, Zhang H, Tang Y, Wang J, Li R, Wen W, Zhang Y

Background: The present investigation explored the therapeutic actions of oleuropein along with the possible signaling pathway involved in attenuating neuropathic pain in chronic constriction injury (CCI) and vincristine-induced neuropathic pain...
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Spermatogenesis of Male Patients with Congenital Hypogonadotropic Hypogonadism Receiving Pulsatile Gonadotropin-Releasing Hormone Therapy Versus Gonadotropin Therapy: A Systematic Review and Meta-Analysis

Wei C, Long G, Zhang Y, Wang T, Wang S, Liu J, Ma D, Liu X

Purpose: Pulsatile gonadotropin-releasing hormone (GnRH) therapy and gonadotropin therapy (GT) were widely used for male patients with congenital hypogonadotropic hypogonadism (CHH), but their efficacy was not well compared before. We...
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Promoting Osseointegration of Dental Implants in Dog Maxillary Sinus Floor Augmentation Using Dentin Matrix Protein 1-Transduced Bone Marrow Stem Cells

Ma D, Wang Y, Chen Y, Yang G, Liu X

BACKGROUND: Beta-tricalcium phosphate ( β-TCP) has been employed successfully as a synthetic graft material in maxillary sinus floor augmentation (MSFA) for placing dental implants. However, the lack of osteogenic and...
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