- Monocrotaline-induced pulmonary hypertension correlates with upregulation of connective tissue growth factor expression in the lung
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Lee YS, Byun J, Kim JA, Lee JS, Kim KL, Suh YL, Kim JM, Jang HS, Lee JY, Shin IS, Suh W, Jeon ES, Kim DK
- KMID: 1033098
- Exp Mol Med.
- 2005 Feb;37(1):27-35.
Pulmonary hypertension (PH) is characterized by structural and functional changes in the lung including proliferation of vascular smooth muscle cells (VSMCs) and excessive collagen synthesis. Although connective tissue growth factor... -
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- Little role of anti-gB antibodies in neutralizing activity of patient's sera with human cytomegalovirus (HCMV) infection
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Park JW, Kim DJ, Kim J, Park CG, Hwang ES, Cha CY
- KMID: 648113
- J Korean Med Sci.
- 2000 Apr;15(2):133-138.
- doi: 10.3346/jkms.2000.15.2.133
Human cytomegalovirus (HCMV) gB is known to play important roles in cell surface attachment, virion penetration, spread of infection from cell to cell, and provocation of neutralizing antibody. This study... -
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- Rapamycin Inhibits Transforming Growth Factor beta1-Induced Fibrogenesis in Primary Human Lung Fibroblasts
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Gao Y, Xu X, Ding K, Liang Y, Jiang D, Dai H
- KMID: 1503908
- Yonsei Med J.
- 2013 Mar;54(2):437-444.
- doi: 10.3349/ymj.2013.54.2.437
PURPOSE: The present study was designed to determine whether rapamycin could inhibit transforming growth factor beta1 (TGF-beta1)-induced fibrogenesis in primary lung fibroblasts, and whether the effect of inhibition would occur... -
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- Induction of fibronectin gene expression by inhibitors of protein phosphatase type 2B in normal and transformed fibroblasts
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Rhew JH, Shin YA, Lee BH, Park RW, Kim IS
- KMID: 1029934
- Exp Mol Med.
- 1999 Jun;31(2):71-75.
Two intracellular signal pathways mediated by cAMP and protein kinase C (PKC) were involved in the regulation of FN gene expression (Lee et al., Exp. Mol. Med. 30: 240, 1998). In this... -
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- Enhancement of protective immune responses by oral vaccination with Saccharomyces cerevisiae expressing recombinant Actinobacillus pleuropneumoniae ApxIA or ApxIIA in mice
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Shin SJ, Shin SW, Kang ML, Lee DY, Yang MS, Jang YS, Yoo HS
- KMID: 1106219
- J Vet Sci.
- 2007 Dec;8(4):383-392.
- doi: 10.4142/jvs.2007.8.4.383
We previously induced protective immune response by oral immunization with yeast expressing the ApxIIA antigen. The ApxI antigen is also an important factor in the protection against Actinobacillus pleuropneumoniae serotype... -
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- Free radical scavenging and antioxidant enzyme fortifying activities of extracts from Smilax china root
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Lee SE, Ju EM, Kim JH
- KMID: 1457540
- Exp Mol Med.
- 2001 Dec;33(4):263-268.
The extract from Smilax china root has been used as medicinal remedy and reported to retain antimicrobial and antimutagenic acitivities. In this study, a possible presence of antioxidant activity of... -
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- Interleukin-1 beta Induces MUC2 Gene Expression and Mucin Secretion via Activation of PKC-MEK/ERK,and PI3K in Human Airway Epithelial Cells
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Kim YD, Jeon JY, Woo HJ, Lee JC, Chung JH, Song SY, Yoon SK, Baek SH
- KMID: 648785
- J Korean Med Sci.
- 2002 Dec;17(6):765-771.
- doi: 10.3346/jkms.2002.17.6.765
Interleukin 1 beta (IL-1 beta), a proinflammatory cytokine, is related with inflammatory diseases and it up-regulates MUC2 gene expression and mucin secretion. This study was designed to investigate the... -
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