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Differential Effect of gamma-radiation-induced Heme Oxygenase-1 Activity in Female and Male C57BL/6 Mice

Han Y, Platonov A, Akhalaia M, Yun YS, Song JY

Ionizing radiation produces reactive oxygen species, which exert diverse biological effects on cells and animals. We investigated alterations of heme oxygenase (HO) and non-protein thiols (NPSH), which are known as...
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Distribution of phospholipase C isozymes in normal human lung tissue and their immunohistochemical localization

Hwang SC, Park KH, Ha MJ, Noh IS, Park TB, Lee YH

Phospholipase C(PLC) plays a central role in signal transduction and it is important in cellular growth, differentiation and transformation. There are currently ten known mammalian isozymes of PLC identified and...
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Lung Matrix Metalloproteinase-9 Correlates with Cigarette Smoking and Obstruction of Airflow

Kang MJ, Oh YM, Lee JC, Kim DG, Park MJ, Lee MG, Hyun IG, Han SK, Shim YS, Jung KS

Cigarette smoking is the most important risk factor for obstruction of airflow in chronic obstructive pulmonary disease (COPD). Matrix metalloproteinases (MMPs) or an imbalance between MMPs and their inhibitors, the...
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