- Hepatitis C virus genotypes in Korea and their relationship to clinical outcome in type C chronic liver diseases
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Han CJ, Lee HS, Kim HS, Choe JH, Kim CY
- KMID: 1038875
- Korean J Intern Med.
- 1997 Jan;12(1):21-27.
OBJECTIVES: The relationship between HCV genotype and the development of more serious liver disease has not been clearly established. This study was to investigate the distribution pattern of HCV genotypes... -
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- Viral loads and E2/NS1 region sequences of hepatitis C virus in hepatocellular carcinoma and surrounding liver
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Park CK, Park TR, Kim YB, Kim HY, Yoo JY, Kim CH, Choo SH, Cho JM
- KMID: 1038874
- Korean J Intern Med.
- 1997 Jan;12(1):28-33.
OBJECTIVES: Numerous epidemiologic data have documented that chronic infection by hepatitis C virus (HCV) is a major risk factor for the development of hepatocellular carcinoma (HCC). But the molecular mechanism... -
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- Distribution of Hepatitis B Virus Genotypes according to the Clinical Outcomes in Patients with Chronic Hepatitis B Virus Infection in Jeju Island
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Kim BJ, Song BC
- KMID: 1066040
- Korean J Gastroenterol.
- 2003 Dec;42(6):496-501.
BACKGROUND/AIMS: The genotype of hepatitis B virus (HBV) has been suggested to correlate with the clinical outcome of HBV infection. We analyzed the distribution of HBV genotypes according to... -
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- Prevalence of viral hepatitis markers in Korean patients with hepatocellular carcinoma
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Huh K, Choi SY, Whang YS, Lee DS
- KMID: 1745555
- J Korean Med Sci.
- 1998 Jun;13(3):306-310.
- doi: 10.3346/jkms.1998.13.3.306
The positive rates of hepatitis B surface antigen (HBsAg) and antibody to hepatitis C virus (anti-HCV) were analyzed according to year, sex, age, and serum ALT levels in 1,370... -
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- Mutations of hepatitis C virus 1b NS5A 2209-2248 amino acid sequence is not a edictive factor for response to interferon-alpha therapy and development of patocellular carcinoma
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Bae SH, Park YM, Yoo DG, Choi JY, Byun BH, Yang JM, Lee CD, Cha SB, Park DH, KiM BS
- KMID: 1731234
- J Korean Med Sci.
- 2000 Feb;15(1):53-58.
- doi: 10.3346/jkms.2000.15.1.53
Genetic changes between codons 2209 and 2248 of NS5A of genotype 1b hepatitis C virus (HCV-1b) have been reported to be associated with the sensitivity to interferon-alpha (IFN-alpha). The present... -
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- Expression of Transforming Growth Factor beta-1 in Chronic Hepatitis and Hepatocellular Carcinoma Associated with Hepatitis C Virus Infection
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Kim HG, Chung YH, Song BC, Kim JA, Yang SH, Lee YS, Suh DJ
- KMID: 759514
- Korean J Intern Med.
- 2000 Dec;15(3):165-170.
BACKGROUND: Transforming growth factor beta-1 (TGF beta 1) has been suggested to play a role in the development, growth or progression of hepatocellular carcinoma (HCC). Genotype and serum titer of... -
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- Analysis of the precore and core promoter DNA sequence in liver tissues from tients with hepatocellular carcinoma
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Cho SW, Shin YJ, Hahm KB, Jin JH, Kim YS, Kim JH, Kim HJ
- KMID: 1731317
- J Korean Med Sci.
- 1999 Aug;14(4):424-430.
- doi: 10.3346/jkms.1999.14.4.424
To investigate the role of mutant hepatitis B virus (HBV) in the development of hepatocellular carcinoma (HCC), 20 patients with HCC were studied for precore and core promoter mutations in... -
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- Localization of hepatitis B virus DNA in hepatocellular carcinoma by polymerase chain reaction in situ hybridization
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Shin YJ, Cho SW, Hahm KB, Kim YS, Kim JH, Park KH, Lee SI
- KMID: 1038164
- J Korean Med Sci.
- 1998 Aug;13(4):377-382.
- doi: 10.3346/jkms.1998.13.4.377
The polymerase chain reaction in situ hybridization (PCR-ISH) is a new technique that combines the sensitivity of PCR with the localizing ability of ISH. To investigate the expression pattern... -
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- The Clinical Significance of Quantitation of HBV DNA in Serum: Comparison of the Branched-DNA Assay with the Second-Generation Digene Hybrid Capture Assay and Long-term Observation
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Jun EJ, Han JY, Choi H, Chang UI, Lee TK, Kim YH, Kim JI, Park SH, Kim JK, Chung KW, Sun HS
- KMID: 1123165
- Korean J Hepatol.
- 2002 Jun;8(2):157-166.
BACKGROUNDS/AIMS: Serum levels of hepatitis B virus (HBV) DNA are direct measures of viral replication in hepatocytes. We compared branched-DNA assay (QuantiplexTM, bDNA) and Hybridization Capture II (HCII), and evaluated... -
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- Precore codon 28 stop mutation in hepatitis B virus from patients with hepatocellular carcinoma
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Park YM, Kim BS, Tabor E
- KMID: 1051572
- Korean J Intern Med.
- 1997 Jun;12(2):201-207.
OBJECTIVES: Hepatitis B virus (HBV) with a stop mutation at precore codon 28 (TGG-->TAG, tryptophan-->stop) was investigated to clarify if such a mutant virus might play a role in hepatocarcinogenesis.... -
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- The Prevalence and Clinical Characteristics of Hepatitis-delta Infection in Korea
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Jeong SH, Kim JM, Ahn HJ, Park MJ, Paik KH, Choi W, Kim J, Han CJ, Kim YC, Lee JO, Hong YJ, Park HY, Jeong HH, Yoon MY, Lee M, Lee KH
- KMID: 760579
- Korean J Hepatol.
- 2005 Mar;11(1):43-50.
BACKGROUND/AIMS: The prevalence of hepatitis delta virus (HDV) infection has been estimated as being approximately 5% among global HBsAg carriers. The anti-delta positive rate in Koreans had been reported... -
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