- Promoter Methylation of E-cadherin in Hepatocellular Carcinomas and Dysplastic Nodules
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Kwon GY, Yoo BC, Koh KC, Cho JW, Park WS, Park CK
- KMID: 1095198
- J Korean Med Sci.
- 2005 Apr;20(2):242-247.
- doi: 10.3346/jkms.2005.20.2.242
In order to clarify the significance of E-cadherin methylation in multistep hepatocarcinogenesis, we examined the methylation status of the E-cadherin promoter region, using methylation-specific polymerase chain reaction in 64 hepatocellular... -
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- Pharmacological Unmasking Microarray Approach-Based Discovery of Novel DNA Methylation Markers for Hepatocellular Carcinoma
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Jung N, Won JK, Kim BH, Suh KS, Jang JJ, Kang GH
- KMID: 1421610
- J Korean Med Sci.
- 2012 Jun;27(6):594-604.
- doi: 10.3346/jkms.2012.27.6.594
DNA methylation is one of the main epigenetic mechanisms and hypermethylation of CpG islands at tumor suppressor genes switches off these genes. To find novel DNA methylation markers in hepatocellular... -
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