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Oxidation-dependent effects of oxidized LDL: proliferation or cell death

Han CY, Kim Pak YM

  • KMID: 1029922
  • Exp Mol Med.
  • 1999 Dec;31(4):165-173.
Oxidized low-density lipoprotein (oxLDL) induces a wide range of cellular responses to produce atherosclerotic lesion, but key factors determining the response are not understood. In this study, purified...
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Nuclear Molecular Imaging for Vulnerable Atherosclerotic Plaques

Lee SJ, Paeng JC

Atherosclerosis is an inflammatory disease as well as a lipid disorder. Atherosclerotic plaque formed in vessel walls may cause ischemia, and the rupture of vulnerable plaque may result in fatal...
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A reconstituted HDL containing V156K or R173C apoA-I exhibited anti-inflammatory activity in apo-E deficient mice and showed resistance to myeloperoxidase-mediated oxidation

Cho KH, Kim JR

It has been hypothesized that blood infusion of reconstituted HDL (rHDL) is a possible therapeutic strategy for the treatment of coronary artery disese. To compare short-term anti-inflammatory activity of wildtype...
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Impact of Lysophosphatidylcholine on the Plasminogen Activator System in Cultured Vascular Smooth Muscle Cells

Yoon BK, Kang YH, Oh WJ, Park K, Lee DY, Choi D, Kim DK, Lee Y, Rhyu MR

The balance between tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1) regulates fibrinolysis. PAI-1 expression increases in atherosclerotic arteries and vascular smooth muscle cells (VSMCs) are one...
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Characterization of Binding and Phagocytosis of Oxidatively Damaged Erythrocyte to Macrophage

Ko HS, Kim IS, Lee KJ, Kim SW, Kim CJ, Ryu WS

  • KMID: 759614
  • Korean J Intern Med.
  • 2002 Dec;17(4):220-226.
BACKGROUND: Scavenger receptors are thought to be involved in the recognition of oxidized low-density lipoprotein (oxLDL) and oxidized erythrocyte (oxRBC). However, there are controversies about the kind of receptors...
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