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Machine Learning and Deep Learning for the Pharmacogenomics of Antidepressant Treatments

Lin E, Lin CH, Lane HY

A growing body of evidence now proposes that machine learning and deep learning techniques can serve as a vital foundation for the pharmacogenomics of antidepressant treatments in patients with major...
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Biomarkers of Irritable Bowel Syndrome

Kim JH, Lin E, Pimentel M

  • KMID: 2367451
  • J Neurogastroenterol Motil.
  • 2017 Jan;23(1):20-26.
  • doi: 10.5056/jnm16135
Traditionally, irritable bowel syndrome (IBS) has not been regarded as an organic disease, and the pathophysiology of IBS is heterogeneous. Currently, the diagnosis of IBS is based upon the Rome...
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Epigenetics and Depression: An Update

Lin E, Tsai SJ

OBJECTIVE: Depression is associated with various environmental risk factors such as stress, childhood maltreatment experiences, and stressful life events. Current approaches to assess the pathophysiology of depression, such as epigenetics...
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Endovascular Therapy in the Extended Time Window for Large Vessel Occlusion in Patients With Pre-Stroke Disability

Tanaka K, Yamagami H, Qureshi MM, Uchida K, Siegler JE, Nogueira RG, Yoshimura S, Sakai N, Martinez-Majander N, Nagel S, Demeestere J, Puetz V, Haussen DC, Abdalkader M, Olive-Gadea M, Mohammaden MH, Marto JP, Dusart A, Winzer S, Tomppo L, Caparros F, Henon H, Bellante F, Ramos JN, Ortega-Gutierrez S, Sheth SA, Nannoni S, Kaesmacher J, Vandewalle L, Salazar-Marioni S, Farooqui M, Virtanen P, Ventura R, Zaidi S, Castonguay AC, Puri AS, Farzin B, Masoud HE, Klein P, Jesser J, Requena M, Dobrocky T, Kaiser DP, Peltola E, Strambo D, Möhlenbruch MA, Lin E, Ringleb PA, Zaidat OO, Cordonnier C, Roy D, Lemmens R, Ribo M, Strbian D, Fischer U, Michel P, Raymond J, Nguyen TN

Background and Purpose We compared the outcomes of endovascular therapy (EVT) in an extended time window in patients with large-vessel occlusion (LVO) between patients with and without pre-stroke disability. Methods In...
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