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Detailed Analysis of Chromosome Aberrations in Human Leukocyte Induced by Anti-malignant Tumor Agent (FT-207)

Hahn S, Kim DS

The anticancer agent's FT-207, N1-(2'-tetrahydrofuryl)-5-fluorouracil, a derivative of 5FU (5-fluorouracil), induced chromosome damage to the human leukocyte was investigated. FT-207 inhibit mitosis and cause chromatid and chromosome breakage and chromatid...
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Effects of mixed leukocyte reaction, hydrocortisone and cyclosporine on expression of leukocyte adhesion molecules by endothelial and mesangial cells

Ihm CG, Hong SP, Park JK, Lee TW, Cho BS, Yang MH, Kim MJ

We investigated the effects of mixed leukocyte reaction (MLR), hydrocortisone (HC) and cyclosporine A (CsA) on the expression of leukocyte adhesion molecules on the mesangial (MC) and endothelial cells (EnC)....
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Phytotherapeutic effects of Echinacea purpurea in gamma-irradiated mice

Abouelella AM, Shahein YE, Tawfik SS, Zahran AM

Echinacea (E.) purpurea herb is commonly known as the purple coneflower, red sunflower and rudbeckia. In this paper, we report the curative efficacy of an Echinacea extract in gamma-irradiated mice....
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Increased levels of multiple forms of dihydrofolate reductase in peripheral blood leucocytes of cancer patients receiving haematopoietic colony-stimulating factors: interim analysis

Iqbal MP, Burney IA, Sultana F, Mehboobali N, Siddiqui T

  • KMID: 1109307
  • Exp Mol Med.
  • 2000 Jun;32(2):84-87.
The precise mechanism whereby granulocytes proliferate when haematopoietic colony stimulating factors (CSFs) are used in neutropenic cancer patients is poorly understood. The purpose of this study was to investigate whether...
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