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Integrative Physiology: Defined Novel Metabolic Roles of Osteocalcin

Kim YS, Paik IY, Rhie YJ, Suh SH

The prevailing model of osteology is that bones constantly undergo a remodeling process, and that the differentiation and functions of osteoblasts are partially regulated by leptin through different central hypothalamic...
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The Expression of Adiponectin Receptors and the Effects of Adiponectin and Leptin on Airway Smooth Muscle Cells

Shin JH, Kim JH, Lee WY, Shim JY

PURPOSE: Obesity is a major risk factor for asthma and it influences airway smooth muscle function and responsiveness. Adiponectin is inversely associated with obesity and its action is mediated through...
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Rac-mediated actin remodeling and myosin II are involved in KATP channel trafficking in pancreatic beta-cells

Han YE, Lim A, Park SH, Chang S, Lee SH, Ho WK

AMP-activated protein kinase (AMPK) is a metabolic sensor activated during metabolic stress and it regulates various enzymes and cellular processes to maintain metabolic homeostasis. We previously reported that activation of...
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Atrophy of brown adipocytes in the adult mouse causes transformation into white adipocyte-like cells

Kim DW, Kim BS, Kwon HS, Kim CG, Lee HW, Choi WH, Kim CG

  • KMID: 1119333
  • Exp Mol Med.
  • 2003 Dec;35(6):518-526.
Adipose tissue is an important endocrine regulator of glucose metabolism and energy homeostasis. Researches have focused on this tissue not only as a target for pharmacotherapy of obesity and insulin...
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Obesity and Gastrointestinal Cancer-related Factor

Kim DJ

Despite a higher incidence and less favorable outcome of malignant tumors in obese patients, much less recognized is the link between obesity and cancer. The mechanism of the association of...
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