- Irisin Regulates the Functions of Hepatic Stellate Cells
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Dong HN, Park SY, Le CT, Choi DH, Cho EH
- KMID: 2508015
- Endocrinol Metab.
- 2020 Sep;35(3):647-655.
- doi: 10.3803/EnM.2020.658
Background: Hepatic stellate cells (HSCs) are known to play a fundamental role in the progression of liver fibrosis. Once HSCs are activated, they are involved in proliferation, migration, and contractility... -
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- Phloretin Ameliorates Succinate-Induced Liver Fibrosis by Regulating Hepatic Stellate Cells
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Le CT, Nguyen G, Park SY, Dong HN, Cho YK, Lee JH, Im SS, Choi DH, Cho EH
- KMID: 2545272
- Endocrinol Metab.
- 2023 Aug;38(4):395-405.
- doi: 10.3803/EnM.2023.1661
Background: Hepatic stellate cells (HSCs) are the major cells which play a pivotal role in liver fibrosis. During injury, extracellular stimulators can induce HSCs transdifferentiated into active form. Phloretin showed... -
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- Succinate Induces Liver Damage and Hepatic Fibrosis in a Mouse Model
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Le CT, Nguyen G, Dong HN, Park SY, Cho YK, Choi DH, Park WS, Lee Y, Lee JY, Cho EH
- KMID: 2536901
- Keimyung Med J.
- 2022 Dec;41(2):84-91.
- doi: 10.46308/kmj.2022.00143
Hepatic stellate cells (HSCs) play a key role in liver fibrosis. Succinate and succinate receptor (GPR91) signaling pathway are involved in the activation, proliferation, and migration of HSCs. We investigated... -
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