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Alterations in Calcium-Activated Potassium Channel Expressions in Human Prostate Cancer

Kim DY, Yang EK, Kim JW

PURPOSE: Recent studies have shown that potassium (K+) and sodium channels are involved in prostate cell growth. However, a great many of the studies have been done in prostate cancer...
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Effects of Phytoestrogen on Potassium Channel Activities of Smooth Muscle Cells of Rabbit Seminal Vesicle

Choi J, Ki SH, Kim YC, Kim TH

  • KMID: 2226602
  • Korean J Androl.
  • 2007 Aug;25(2):72-78.
PURPOSE: This study was performed to determine the effects of phytoestrogen on seminal vesicle excitability. MATERIALS AND METHODS: Single smooth muscle cells of seminal vesicle were obtained from rabbits using...
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The large-conductance calcium-activated potassium channel holds the key to the conundrum of familial hypokalemic periodic paralysis

Kim JB, Kim SJ, Kang SY, Yi JW, Kim SM

PURPOSE: Familial hypokalemic periodic paralysis (HOKPP) is an autosomal dominant channelopathy characterized by episodic attacks of muscle weakness and hypokalemia. Mutations in the calcium channel gene, CACNA1S, or the sodium...
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Increased activity of large conductance Ca2+-activated K+ channels in negatively-charged lipid membranes

Park JB, Ryu PD

  • KMID: 2285216
  • Korean J Physiol Pharmacol.
  • 1998 Aug;2(4):529-539.
The effects of membrane surface charge originated from lipid head groups on ion channels were tested by analyzing the activity of single large conductance Ca2+-activated K+ (maxi K) channel from rat skeletal muscle....
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Characterization of Intermediate Conductance K+ Channels in Submandibular Gland Acinar Cells

Cho SM, Piao ZG, Kim YB, Kim JS, Park K

  • KMID: 1615197
  • Korean J Physiol Pharmacol.
  • 2002 Dec;6(6):305-309.
There are some evidences that K+ efflux evoked by muscarinic stimulation is not mainly mediated by large conductance K+ (BK) channels in salivary gland. In this experiment, we therefore characterised...
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The Effects of Sex Steroids on the Maxi-K Channel Activity of Human Vas Deferens

Myung SC, Lee MY, Cho SH, Yang CS

  • KMID: 2294038
  • Korean J Urol.
  • 2005 Aug;46(8):867-872.
Purpose: We investigated the effects of sex steroids on the maxi-K channel activities of the single smooth muscle cells of the human vas deferens. Materials and Methods: Human vas deferens cells...
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Quercetin-induced Growth Inhibition in Human Bladder Cancer Cells Is Associated with an Increase in Ca(2+)-activated K+ Channels

Kim Y, Kim WJ, Cha EJ

Quercetin (3,3',4',5,7-pentahydroxyflavone) is an attractive therapeutic flavonoid for cancer treatment because of its beneficial properties including apoptotic, antioxidant, and antiproliferative effects on cancer cells. However, the exact mechanism of action...
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The Effects of Ethanol and Acetaldehyde on Corpus Cavernosal Smooth Muscle of the Rabbit

Lee KR, Bae JH, Kim JW, Shim KS, Oh MM, Park MG, Moon DG, Kim JJ

  • KMID: 2298727
  • Korean J Androl.
  • 2009 Dec;27(3):170-176.
PURPOSE: This study is to assess the pharmacologic effects of ethanol and its metabolite, acetaldehyde on potassium channels of the corpus cavernosal smooth muscle of the rabbit. MATERIALS AND METHODS: Cavernosal...
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