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Identification and HPLC Quantification of a Phytoecdysone and Three Phenolic Glycosides in Lamium takesimense Nakai

Nugroho A, Park KS, Seo DJ, Park HJ

The herbs of Lamium takesimense Nakai (Lamiaceae) is used to treat spasmodic and inflammatory disease. The four polar compounds, ecdysterone, isoacteoside, rutin and lamiuside C, were isolated and identified from...
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Isolation of Flavonoid Glycosides with Cholinesterase Inhibition Activity and Quantification from Stachys japonica

Nugroho A, Choi JS, Seong SH, Song BM, Park KS, Park HJ

The three flavone glycosides, 4′-O-methylisoscutellarein 7-O-(6‴-O-acetyl)-β-D-allopyranosyl(1→2)-β-D-glucopyranoside (1), isoscutellarein 7-O-(6‴-O-acetyl)-β-D-allopyranosyl(1→2)-β-D-glucopyranoside (3), and isoscutellarein 7-O-β-D-allopyranosyl(1→2)-β-D-glucopyranoside (4) in addition to a flavonol glycoside, kaempferol 3-O-β-D-glucopyranoside (astragalin, 2), were isolated from Stachys japonica (Lamiaceae)....
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Effects of rosmarinic acid on immunoregulatory activity and hepatocellular carcinoma cell apoptosis in H22 tumor-bearing mice

Cao W, Mo K, Wei S, Lan X, Zhang W, Jiang W

Rosmarinic acid (RA) is a natural polyphenolic compound that exists in many medicinal species of Boraginaceae and Lamiaceae. The previous studies have revealed that RA had therapeutic effects on hepatocellular...
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Therapeutic effect of oregano essential oil on subclinical bovine mastitis caused by Staphylococcus aureus and Escherichia coli

Cho BW, Cha CN, Lee SM, Kim MJ, Park JY, Yoo CY, Son SE, Kim S, Lee HJ

Oregano (Origanum vulgare) is an aromatic herb belonging to the Lamiaceae family. This study evaluated the therapeutic effect of oregano essential oil (OEO) on clinical bovine mastitis caused by Staphylococcus...
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Pain and Paresthesia after Ingestion of Glechoma Longituba: Three Case Reports

Park CW, Cho JH, Bae JH, Moon JB, Cheon SB, Ahn KO, Lee HY

  • KMID: 1818927
  • J Korean Soc Emerg Med.
  • 2011 Aug;22(4):359-361.
Glechoma longituba is a common medicinal plant that is common in wet and sunny land. This plant is used to treat various illnesses including jaundice and edema. But, ingestion of...
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Protective Effect of HP08-0106 on Ligature-induced Periodontitis in Rats

Choi HJ, Cho HK, Soh Y

  • KMID: 1445160
  • Int J Oral Biol.
  • 2011 Dec;36(4):187-194.
Periodontitis is an inflammatory disorder of the periodontium, characterized by destruction of the tooth supporting tissues including alveolar bone and mediated by various pro-inflammatory mediators. Here, we demonstrated that HP08-0106,...
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Screening of Anti-HIV-1 Activity of Natural Product by MTT Assay

Lee JS, Nam JG, Kang C, Lee HR, Lee YJ, Shin YO

  • KMID: 2204569
  • J Korean Soc Virol.
  • 1997 Mar;27(1):87-95.
Methanol and/or boiling water extraction of 201 natural products and subsequent MTT assay using MT-4 cell line was carried out to screen the anti-HIV-1 activity. Among 97 methanol extracts, 7...
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Tanshinone IIA, an ingredient of Salvia miltiorrhiza BUNGE, induces apoptosis in human leukemia cell lines through the activation of caspase-3

Sung HJ, Choi SM, Yoon YS, An KS

  • KMID: 1029923
  • Exp Mol Med.
  • 1999 Dec;31(4):174-178.
Tanshinone II-A is a derivative of phenanthrene-quinone isolated from Salvia miltiorrhiza BUNGE, a traditional herbal medicine that is known to induce antiinflammatory, anti-oxidative and cytotoxic activity. We have...
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