- The feasibility of detecting endometrial and ovarian cancer using DNA methylation biomarkers in cervical scrapings
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Chang CC, Wang HC, Liao YP, Chen YC, Weng YC, Yu MH, Lai HC
- KMID: 2395244
- J Gynecol Oncol.
- 2018 Jan;29(1):e17.
- doi: 10.3802/jgo.2018.29.e17
OBJECTIVE: We hypothesized that DNA methylation of development-related genes may occur in endometrial cancer (EC)/ovarian cancer (OC) and may be detected in cervical scrapings. METHODS: We tested methylation status by quantitative... -
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- Bupropion for Interferon-Alpha-Induced Depression in Patients with Hepatitis C Viral Infection: An Open-Label Study
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Chen WC, Lai HC, Su WP, Palani M, Su KP
- KMID: 2316400
- Psychiatry Investig.
- 2015 Jan;12(1):142-145.
- doi: 10.4306/pi.2015.12.1.142
Interferon (IFN)-alpha therapy for chronic hepatitis C virus (HCV) infection is frequently associated with major depressive episodes. Bupropion, a commonly used antidepressant agent, has recently found to have strong anti-inflammatory... -
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- Genotype-specific methylation of HPV in cervical intraepithelial neoplasia
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Hsu YW, Huang RL, Su PH, Chen YC, Wang HC, Liao CC, Lai HC
- KMID: 2413439
- J Gynecol Oncol.
- 2017 Jul;28(4):e56.
- doi: 10.3802/jgo.2017.28.e56
OBJECTIVE: Hypermethylation of human papillomavirus (HPV) and host genes has been reported in cervical cancer. However, the degree of methylation of different HPV types relative to the severity of the... -
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- Effective Antiviral Activity of the Tyrosine Kinase Inhibitor Sunitinib Malate against Zika Virus
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Lin CS, Huang SH, Yan BY, Lai HC, Lin CW
- KMID: 2524056
- Infect Chemother.
- 2021 Dec;53(4):730-740.
- doi: 10.3947/ic.2021.0111
Background:(Introduction): Zika virus (ZIKV), a mosquito-borne flavivirus, causes the outbreaks of Latin America in 2015 - 2016, with the incidence of neurological complications. Sunitinib malate, an orally bioavailable malate salt... -
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- Metformin and statins reduce hepatocellular carcinoma risk in chronic hepatitis C patients with failed antiviral therapy
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Tsai PC, Huang CF, Yeh ML, Hsieh MH, Kuo HT, Hung CH, Tseng KC, Lai HC, Peng CY, Wang JH, Chen JJ, Lee PL, Chien RN, Yang CC, Lo GH, Kao JH, Liu CJ, Liu CH, Yan SL, Lin CY, Su WW, Chu CH, Chen CJ, Tung SY, Tai C, Lin CW, Lo CC, Cheng PN, Chiu YC, Wang CC, Cheng JS, Tsai WL, Lin HC, Huang YH, Chen CY, Huang JF, Dai CY, Chung WL, Bair MJ, Yu ML, T-COACH Study Group
- KMID: 2557396
- Clin Mol Hepatol.
- 2024 Jul;30(3):468-486.
- doi: 10.3350/cmh.2024.0038
Background/Aims: Chronic hepatitis C (CHC) patients who failed antiviral therapy are at increased risk for hepatocellular carcinoma (HCC). This study assessed the potential role of metformin and statins, medications for... -
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- Sofosbuvir/velpatasvir plus ribavirin for Child-Pugh B and Child-Pugh C hepatitis C virus-related cirrhosis
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Liu CH, Chen CY, Su WW, Liu CJ, Lo CC, Huang KJ, Chen JJ, Tseng KC, Chang CY, Peng CY, Shih YL, Huang CS, Kao WY, Yang SS, Tsai MC, Wu JH, Chen PY, Su PY, Hwang JJ, Fang YJ, Lee PL, Tseng CW, Lee FJ, Lai HC, Hsieh TY, Chang CC, Chang CH, Huang YJ, Kao JH
- KMID: 2520841
- Clin Mol Hepatol.
- 2021 Oct;27(4):575-588.
- doi: 10.3350/cmh.2021.0155
Background/Aims: Real-world studies assessing the effectiveness and safety of sofosbuvir/velpatasvir (SOF/VEL) plus ribavirin (RBV) for Child-Pugh B/C hepatitis C virus (HCV)-related cirrhosis are limited. Methods: We included 107 patients with Child-Pugh... -
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