- Guidelines for planning and conducting high-quality research and testing on animals
-
Smith AJ
- KMID: 2507222
- Lab Anim Res.
- 2020 Sep;36(3):146-151.
- doi: 10.1186/s42826-020-00054-0
There are important scientific, legal and ethical reasons for optimising the quality of animal research and testing. Concerns about the reproducibility and translatability of animal studies are now being voiced... -
- CITED
-
- Close
- SHARE
-
- Close
- Cryopreservation of mouse resources
-
Takeo T, Nakao S, Nakagawa Y, Sztein JM, Nakagata N
- KMID: 2507223
- Lab Anim Res.
- 2020 Sep;36(3):152-157.
- doi: 10.1186/s42826-020-00066-w
The cryopreservation of sperm and embryos is useful to efficiently archive valuable resources of genetically engineered mice. Till date, more than 60,000 strains of genetically engineered mice have been archived... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparative analysis of restraint stress-induced depressive-like phenotypes in C57BL/6N mice derived from three different sources
-
Hwang DJ, Kwon KC, Hwang DY, Seo MS, Kim KS, Jung YS, Cho JY
- KMID: 2507237
- Lab Anim Res.
- 2020 Sep;36(3):239-247.
- doi: 10.1186/s42826-020-00062-0
C57BL/6NKorl mice are a novel mouse stock recently developed by the National Institute of Food and Drug Safety Evaluation in Korea. Extensive research into the nature of C57BL/6NKorl mice is... -
- CITED
-
- Close
- SHARE
-
- Close
- Study of ethion and lipopolysaccharide interaction on lung in a mouse model
-
Verma G, Sethi RS
- KMID: 2507225
- Lab Anim Res.
- 2020 Sep;36(3):167-176.
- doi: 10.1186/s42826-020-00055-z
Ethion is an organophosphate used commonly in India despite being banned in many other countries. The present study was designed to study the interaction of ethion and lipopolysaccharide (LPS) together... -
- CITED
-
- Close
- SHARE
-
- Close
- Influence of three BALB/c substrain backgrounds on the skin tumor induction efficacy to DMBA and TPA cotreatment
-
Kang MJ, Gong JE, Kim JE, Choi HJ, Bae SJ, Seo MS, Kim KS, Jung YS, Cho JY, Lim Y, Hwang DY
- KMID: 2507238
- Lab Anim Res.
- 2020 Sep;36(3):248-259.
- doi: 10.1186/s42826-020-00063-z
Differences in responsiveness of BALB/c substrains have been investigated in various fields, including diabetes induction, corpus callosum deficiency, virus-induced demyelinating disease, aggressive behavior and osteonecrosis. However, induction efficacy of skin... -
- CITED
-
- Close
- SHARE
-
- Close
- Two base pair deletion in IL2 receptor γ gene in NOD/SCID mice induces a highly severe immunodeficiency
-
Bak I, Kim DJ, Kim HC, Shin HJ, Yu E, Yoo KW, Yu DY
- KMID: 2507233
- Lab Anim Res.
- 2020 Sep;36(3):218-228.
- doi: 10.1186/s42826-020-00048-y
Genome editing has recently emerged as a powerful tool for generating mutant mice. Small deletions of nucleotides in the target genes are frequently found in CRISPR/Cas9 mediated mutant mice. However,... -
- CITED
-
- Close
- SHARE
-
- Close
- Tamoxifen-inducible cardiac-specific Cre transgenic mouse using VIPR2 intron
-
Chin HJ, Lee Sy, Lee D
- KMID: 2507239
- Lab Anim Res.
- 2020 Sep;36(3):260-267.
- doi: 10.1186/s42826-020-00065-x
Genetically engineered mouse models through gene deletion are useful tools for analyzing gene function. To delete a gene in a certain tissue temporally, tissue-specific and tamoxifen-inducible Cre transgenic mice are... -
- CITED
-
- Close
- SHARE
-
- Close
- Decrease of protein phosphatase 2A subunit B by glutamate exposure in the cerebral cortex of neonatal rats
-
Kang JB, Park DJ, Son HK, Koh PO
- KMID: 2507241
- Lab Anim Res.
- 2020 Sep;36(3):279-287.
- doi: 10.1186/s42826-020-00064-y
Glutamate induces neurotoxicity during brain development, causing nerve damage. Protein phosphatase 2A (PP2A) is a type of serine/threonine phosphatase that regulates various biological functions. Among the PP2A subunit types, subunit... -
- CITED
-
- Close
- SHARE
-
- Close
- Characterization of changes in global gene expression in the hearts and kidneys of transgenic mice overexpressing human angiotensin-converting enzyme 2
-
Lee SH, Jee SW, Hwang DY, Kang JK
- KMID: 2507226
- Lab Anim Res.
- 2020 Sep;36(3):177-187.
- doi: 10.1186/s42826-020-00056-y
Human angiotensin-converting enzyme 2 (hACE2) has recently received a great attention due to it play a critical role as SARS-CoV receptor in the infection of human body. However, no further... -
- CITED
-
- Close
- SHARE
-
- Close
- High fat diet accelerates and exacerbates microgliosis and neuronal damage/death in the somatosensory cortex after transient forebrain ischemia in gerbils
-
Seo WJ, Ahn JH, Lee TK, Kim B, Lee JC, Park JH, Yoo YH, Shin MC, Cho JH, Won MH, Park Y
- KMID: 2507236
- Lab Anim Res.
- 2020 Sep;36(3):229-238.
- doi: 10.1186/s42826-020-00061-1
Obesity has been known as an independent risk factor for stroke. Effects of high-fat diet (HFD)-induced obesity on neuronal damage in the somatosensory cortex of animal models of cerebral ischemia... -
- CITED
-
- Close
- SHARE
-
- Close
- Changes of fat-mass and obesity-associated protein expression in the hippocampus in animal models of high-fat diet-induced obesity and D-galactose-induced aging
-
Kang MS, Kim TH, Choi JH, Kim W, Jung HY, Hwang IK, Kim W, Kwon HJ, Kim DW
- KMID: 2507224
- Lab Anim Res.
- 2020 Sep;36(3):158-166.
- doi: 10.1186/s42826-020-00046-0
Fat-mass and obesity-associated protein (Fto) is highly expressed in the brain including, the hippocampus, and its expression is significantly decreased in the brain of Alzheimer’s disease patients. In the present... -
- CITED
-
- Close
- SHARE
-
- Close
- Quisqualis indica extract ameliorates low urinary tract symptoms in testosterone propionate-induced benign prostatic hyperplasia rats
-
Kim Dg, Kim Jh, Kwon HJ, Lim JH, Lee KP
- KMID: 2507230
- Lab Anim Res.
- 2020 Sep;36(3):208-217.
- doi: 10.1186/s42826-020-00059-9
Benign prostate hyperplasia (BPH) is a common disease in old-age males, accounting for approximately 77% of morbidity within the age range of 40 to 70 years. It has been shown that... -
- CITED
-
- Close
- SHARE
-
- Close
- Early high-fat feeding improves histone modifications of skeletal muscle at middle-age in mice
-
Yoshie T, Saito C, Kawano F
- KMID: 2507228
- Lab Anim Res.
- 2020 Sep;36(3):197-207.
- doi: 10.1186/s42826-020-00060-2
The purpose of the present study was to investigate how the effects of high-fat diet feeding on the skeletal muscle persisted during aging using mice. Post-weaned male mice were fed... -
- CITED
-
- Close
- SHARE
-
- Close
- Degenerative joint disease in the temporomandibular joint with fibrous ankylosis in a rhesus macaque (Macaca mulatta)
-
Kim SM, Woo CG, Kim JM
- KMID: 2507242
- Lab Anim Res.
- 2020 Sep;36(3):288-292.
- doi: 10.1186/s42826-020-00052-2
Background Ankylosis in the temporomandibular joint (TMJ) is known to have various etiologies in veterinary medicine. We observed a case of fibrous ankylosis of the TMJ in a newly imported rhesus... -
- CITED
-
- Close
- SHARE
-
- Close
- Baicalin alleviates lipopolysaccharide-induced neuroglial activation and inflammatory factors activation in hippocampus of adult mice
-
Shah MA, Park DJ, Kang JB, Koh PO, Kim MO
- KMID: 2507240
- Lab Anim Res.
- 2020 Sep;36(3):268-278.
- doi: 10.1186/s42826-020-00058-w
Baicalin is a natural flavonoid that exerts a variety of pharmaceutical effects such as anti-inflammatory and antioxidant. Lipopolysaccharide (LPS) is an endotoxin that releases inflammatory cytokines and induces inflammatory response.... -
- CITED
-
- Close
- SHARE
-
- Close
- Brain Factor-7® improves learning and memory deficits and attenuates ischemic brain damage by reduction of ROS generation in stroke in vivo and in vitro
-
Noh Y, Lee JW, Hong J, Kim SS, Ahn JH, Lee TK, Kim B, Won MH
- KMID: 2507227
- Lab Anim Res.
- 2020 Sep;36(3):188-196.
- doi: 10.1186/s42826-020-00057-x
Brain Factor-7® (BF-7), silk fibroin peptide, is known to be effective in improvement of memory and learning ability. In this study, the effects of BF-7 (10 mg/kg, p.o., pre-treatment for 7 days... -
- CITED
-
- Close
- SHARE
-
- Close
