- Characterization and applications of chimeric mice with humanized livers for preclinical drug development
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Tateno C, Kojima Y
- KMID: 2510419
- Lab Anim Res.
- 2020 Mar;36(1):11-19.
- doi: 10.1186/s42826-019-0032-y
We have succeeded in stable mass production of chimeric PXB-mice, whose liver is repopulated by human hepatocytes at a ratio of more than 70%, and we are providing these mice... -
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- A comparison of the metabolic effects of treadmill and wheel running exercise in mouse model
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Kim YJ, Kim HJ, Lee WJ, Seong JK
- KMID: 2510420
- Lab Anim Res.
- 2020 Mar;36(1):20-27.
- doi: 10.1186/s42826-019-0035-8
Aerobic exercise is well known to have a positive impact on body composition, muscle strength, and oxidative capacity. In animal model, both treadmill and wheel running exercise modalities have become... -
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- Characterization of aged male BALB/ccenp mice as a model of dementia
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Esquivel N, García Y, Lores B, Gutiérrez M, Rodríguez C
- KMID: 2510423
- Lab Anim Res.
- 2020 Mar;36(1):46-55.
- doi: 10.1186/s42826-020-00038-0
Dementia is defined as cognitive impairment in more than one cognitive area and leads to an abnormal degree of impairment in the ability to remember past events. Among mice models... -
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- Compensatory role of C3 convertase on the strain difference for C3 protein expression in FVB/N, C3H/HeN and C57BL/6N mice
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Park JW, Kim JE, Kang MJ, Choi HJ, Bae SJ, Hwang DY
- KMID: 2510421
- Lab Anim Res.
- 2020 Mar;36(1):28-35.
- doi: 10.1186/s42826-020-0036-7
To investigate the role of complement C3 (C3) convertase on the strain difference for C3 protein expression in three inbred mice strains, we compared the levels of C2, C3 and... -
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- Evaluation of factors related to Anaesthesia-induced Lens opacity in experimental mice
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Lee H, Kim HK, Shin HS, Han SJ, Yoon S, Seong JK, Seo KY
- KMID: 2510418
- Lab Anim Res.
- 2020 Mar;36(1):1-10.
- doi: 10.1186/s42826-019-0031-z
To investigate conditions that cause temporal lens opacity, we tested chemical and physical factors, such as anaesthesia dose, ocular surface dryness, and infrared (IR) light exposure in anaesthetised C57BL/6 N mice.... -
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- Relevance of reactive oxygen species in liver disease observed in transgenic mice expressing the hepatitis B virus X protein
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Yu DY
- KMID: 2510422
- Lab Anim Res.
- 2020 Mar;36(1):36-45.
- doi: 10.1186/s42826-020-00037-1
The hepatitis B virus (HBV) infects approximately 240 million people worldwide, causing chronic liver disease (CLD) and liver cancer. Although numerous studies have been performed to date, unfortunately there is... -
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