Skip Navigation
Skip to contents
Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

11 results
Display

The ‘R’ principles in laboratory animal experiments

Lee KH, Lee DW, Kang BC

Since the Three Rs of replacement, reduction and refinement was proposed by Russel and Birch in 1959, researchers have a moral duty to minimize harm to animals. Even though animal...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Comparative analysis of immune related genes between domestic pig and germ-free minipig

Lee JY, Kim SE, Lee HT, Hwang JH

Recently, minipig has been considered as an animal model that is appropriate for human disease model to study toxicology, pharmacology, and xenotransplantation. Nevertheless, minipigs are bred in various environment according...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Extensive variability in the composition of immune infiltrate in different mouse models of cancer

Niemi V, Gaskarth D, Kemp RA

Mouse models are invaluable tools for cancer immunology research. However, there are differences in the immune response to the tumour depending on the model used, and these differences are not...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Evaluation of skin phototoxicity of transdermally administered pharmaceuticals in Sprague-Dawley rats

Youn NH, Kim EJ, Yi JS, Kim JH, Cho YJ, Nam KT, Park KS, Lee JK

Some drugs cause phototoxicity in humans when exposed to light, thus there is a need for an in vivo phototoxicity test to evaluate them. However, an in vivo phototoxicity test...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Impaired liver regeneration and lipid homeostasis in CCl4 treated WDR13 deficient mice

Mishra AP, Siva AB, Gurunathan C, Komala Y, Lakshmi BJ

WDR13 - a WD repeat protein, is abundant in pancreas, liver, ovary and testis. Absence of this protein in mice has been seen to be associated with pancreatic β-cell proliferation,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Anti-Helicobacter pylori activity of acomplex mixture of Lactobacillus paracasei HP7 including the extract of Perilla frutescens var. acuta and Glycyrrhiza glabra

Lee HA, Kim JY, Kim J, Nam B, Kim O

The effect of standard therapeutic strategies on Helicobacter pylori infection is diminished over time owing to the emergence of drug resistant strains. In this study, we would like to confirm...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A comparative study of the phenotype with kainic acid-induced seizure in DBA/2 mice from three different sources

Kang KK, Kim YI, Seo MS, Sung SE, Choi JH, Lee S, Jung YS, Cho JY, Hwang DY, Park SJ, Kim KS

The kainic acid-induced seizure mouse model is widely used in epilepsy research. In this study, we applied kainic acid to the subcutaneous injections of three different sources of DBA/2 mice...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Pathogenicity of severe fever with thrombocytopenia syndrome virus in mice regulated in type I interferon signaling Severe fever with thrombocytopenia and type I interferon

Park SC, Park JY, Choi JY, Lee SG, Eo SK, Oem JK, Tark DS, You M, Yu DH, Chae JS, Kim B

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging zoonotic disease, which causes high fever, thrombocytopenia, and death in humans and animals in East Asian countries. The pathogenicity of SFTS...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Refining drug administration in a murine model of acute infection with Trypanosoma cruzi

Nicolás Gulin JE, Bisio M, García-Bournissen F

Background: In animal research, “refinement” refers to modifications of husbandry or experimental procedures to enhance animal well-being and minimize or eliminate pain and distress. Evaluation of drug efficacy in mice...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Unexpected effects of ivermectin and selamectin on inducible Cre ER activity in mice

Kropp PA, Rushing GV, Brockman AA, Yu ENZ, Ihrie RA, Gannon M

Background: Anti-parasitics are frequently used in research animal facilities to treat a multitude of common infections, with pinworms and fur mites being amongst the most common. Ivermectin and selamectin are...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Correction to: Influence of three BALB/c substrain backgrounds on the skin tumor induction efficacy to DMBA and TPA cotreatment

Kang MJ, Gong JE, Kim JE, Choi HJ, Bae SJ, Choi YJ, Lee SJ, Seo MS, Kim KS, Jung YS, Cho JY, Lim Y, Hwang DY

CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr