- The effects of coenzyme Qâ‚â‚€ supplement on blood lipid indices and hepatic antioxidant defense system in SD rats fed a high cholesterol diet
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Kim HN, Jeon DG, Lim Y, Jang IS
- KMID: 2470112
- Lab Anim Res.
- 2019 Aug;35(2):86-93.
- doi: 10.1186/s42826-019-0013-1
A total of 24 SD rats were allotted to four treatment groups such as the control (CON), 1% of cholesterol diet (CHO), 0.5% of coenzyme Qâ‚â‚€ (COQ) and 1% of... -
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- Comparative analysis of dose-dependent neurotoxic response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 N mice derived from three different sources
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Hwang DJ, Kwon KC, Song HK, Kim KS, Jung YS, Hwang DY, Cho JY
- KMID: 2470109
- Lab Anim Res.
- 2019 Aug;35(2):61-69.
- doi: 10.1186/s42826-019-0012-2
MPTP, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is commonly used to induce nigrostriatal defects to induce parkinsonism and/or parkinsonian syndrome, to replicate the lesions seen in Parkinson's disease (PD), with use in numerous PD models... -
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- Aged mice show an increased mortality after anesthesia with a standard dose of ketamine/xylazine
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Schuetze S, Manig A, Ribes S, Nau R
- KMID: 2470107
- Lab Anim Res.
- 2019 Aug;35(2):45-51.
- doi: 10.1186/s42826-019-0008-y
Geriatric animal models are crucial for a better understanding and an improved therapy of age-related diseases. We observed a high mortality of aged mice after anesthesia with a standard dose... -
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- Comparison study of the response with botulinum toxin muscle injection in the ICR mice from three different sources
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Seo MS, Kim YI, Kang KK, Oh SK, Sung SE, Jung YS, Cho JY, Song H, Hwang DY, Park SJ, Kim KS
- KMID: 2470110
- Lab Anim Res.
- 2019 Aug;35(2):70-77.
- doi: 10.1186/s42826-019-0010-4
Botulinum-toxin A (BoNT/A) is a widely used not only for cosmetics but also for various experimental purposes including muscle-related research. In this study, we applied BoNT/A to mouse muscle of... -
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- Reference values of hematological and biochemical parameters in young-adult cynomolgus monkey (Macaca fascicularis) and rhesus monkey (Macaca mulatta) anesthetized with ketamine hydrochloride
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Koo BS, Lee DH, Kang P, Jeong KJ, Lee S, Kim K, Lee Y, Huh JW, Kim YH, Park SJ, Jin YB, Kim SU, Kim JS, Son Y, Lee SR
- KMID: 2470106
- Lab Anim Res.
- 2019 Aug;35(2):39-44.
- doi: 10.1186/s42826-019-0006-0
Nonhuman primate models are valuable in biomedical research. However, reference data for clinical pathology parameters in cynomolgus and rhesus monkeys are limited. In the present study, we established hematologic and... -
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- Comparative study of liver injury induced by high-fat methionine- and choline-deficient diet in ICR mice originating from three different sources
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Lee S, Kwak JH, Kim SH, Jeong TB, Son SW, Kim JH, Lim Y, Cho JY, Hwang DY, Kim KS, Jung YS
- KMID: 2470114
- Lab Anim Res.
- 2019 Aug;35(2):100-106.
- doi: 10.1186/s42826-019-0016-y
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide. It is characterized by the accumulation of lipids without alcohol intake and often progresses to non-alcoholic... -
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- Correlation between synthesis of α2-macroglobulin as acute phase protein and degree of hepatopathy in rats
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Ito R, Kuribayashi T
- KMID: 2470113
- Lab Anim Res.
- 2019 Aug;35(2):94-99.
- doi: 10.1186/s42826-019-0014-0
The degree of hepatopathy affecting the synthesis of α2-macroglobulin (α2M) as an acute phase protein in rats was investigated. Hepatopathy was induced in Sprague-Dawley rats by intravenous administration of galactosamine... -
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- RbAp48 expression and neuronal damage in the gerbil hippocampus following 5 min of transient ischemia
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Park JH, Lee TK, Kim DW, Park CW, Park YE, Kim B, Lee JC, Lee HA, Won MH, Ahn JH
- KMID: 2470111
- Lab Anim Res.
- 2019 Aug;35(2):78-85.
- doi: 10.1186/s42826-019-0011-3
Histone-binding protein RbAp48 has been known to be involved in histone acetylation, and epigenetic alterations of histone modifications are closely associated with the pathogenesis of ischemic reperfusion injury. In the... -
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- Metabolomics approach to serum biomarker for laxative effects of red Liriope platyphylla in loperamide-induced constipation of SD rats
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Kim JE, Lee YJ, Ryu SH, Park JW, Kang MJ, Choi HJ, Bae SJ, Choi Y, Kang HG, Kim KB, Kim S, Lim Y, Hwang DY
- KMID: 2470108
- Lab Anim Res.
- 2019 Aug;35(2):52-60.
- doi: 10.1186/s42826-019-0009-x
Red Liriope platyphylla (RLP) is a known herbal medicine used in the treatment of some chronic diseases including constipation, neurodegenerative disorders, diabetes and obesity. To determine and characterize putative biomarkers... -
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- Tracking acute phase protein response during acute and chronic Toxoplasma gondii infection
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Atmaca HT, Gazyagci A, Terzi OS, Dincel GC, Sumer T
- KMID: 2470105
- Lab Anim Res.
- 2019 Aug;35(2):30-38.
- doi: 10.1186/s42826-019-0007-z
Toxoplasmosis is a disease caused by the protozoan Toxoplasma gondii, which occurs worldwide in mammals and birds. Brain is the primary target organ because Toxoplasma gondii is a ubiquitous intracellular... -
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