- KLF4 Expression Correlates with the Degree of Differentiation in Colorectal Cancer
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Hu R, Zuo Y, Zuo L, Liu C, Zhang S, Wu Q, Zhou Q, Gui S, Wei W, Wang Y
- KMID: 2135086
- Gut Liver.
- 2011 Jun;5(2):154-159.
BACKGROUND/AIMS: Kruppel-like factor 4 (KLF4) is an epithelial-specific transcription factor primarily expressed in the gastrointestinal tract that mediates growth arrest in the colonic epithelium. We tried to find whether KLF4... -
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- Establishment of Hepatocellular Cancer Induced Pluripotent Stem Cells Using a Reprogramming Technique
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Kim HJ, Jeong J, Park S, Jin YW, Lee SS, Lee SB, Choi D
- KMID: 2412193
- Gut Liver.
- 2017 Mar;11(2):261-269.
- doi: 10.5009/gnl15389
BACKGROUND/AIMS: Cancer is known to be a disease by many factors. However, specific results of reprogramming by pluripotency-related transcription factors remain to be scarcely reported. Here, we verified potential effects... -
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- Kruppel-like factor 4 mediates lysophosphatidic acid-stimulated migration and proliferation of PC3M prostate cancer cells
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Shin SH, Kwon YW, Heo SC, Jeong GO, Kim BR, Seo EJ, Kim JH
- KMID: 2155369
- Exp Mol Med.
- 2014 Jul;46(7):e104.
- doi: 10.1038/emm.2014.34
Prostate cancer is the most frequently diagnosed malignancy and the second leading cause of cancer mortality among men in the United States. Accumulating evidence suggests that lysophosphatidic acid (LPA) serves... -
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- Constitutive stabilization of hypoxia-inducible factor alpha selectively promotes the self-renewal of mesenchymal progenitors and maintains mesenchymal stromal cells in an undifferentiated state
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Park IH, Kim KH, Choi HK, Shim JS, Whang SY, June Hahn , Kwon OJ, Oh IH
- KMID: 2154263
- Exp Mol Med.
- 2013 Sep;45(9):e44.
With the increasing use of culture-expanded mesenchymal stromal cells (MSCs) for cell therapies, factors that regulate the cellular characteristics of MSCs have been of major interest. Oxygen concentration has been... -
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- Replication of the results of genome-wide and candidate gene association studies on telomere length in a Korean population
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Do SK, Yoo SS, Choi YY, Choi JE, Jeon HS, Lee WK, Lee SY, Lee J, Cha SI, Kim CH, Park JY
- KMID: 2381571
- Korean J Intern Med.
- 2015 Sep;30(5):719-726.
- doi: 10.3904/kjim.2015.30.5.719
BACKGROUND/AIMS: A number of genome-wide and candidate gene association studies have identified polymorphisms associated with telomere length in Caucasian populations. This study was conducted to determine the impacts of 17... -
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- Identification of DNA methylation associated gene signatures in endometrial cancer via integrated analysis of DNA methylation and gene expression systematically
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Men C, Chai H, Song X, Li Y, Du H, Ren Q
- KMID: 2413209
- J Gynecol Oncol.
- 2017 Nov;28(6):e83.
- doi: 10.3802/jgo.2017.28.e83
OBJECTIVE: Endometrial cancer (EC) is a common gynecologic cancer worldwide. However, the pathogenesis of EC has not been epigenetically elucidated. Here, this study aims to describe the DNA methylation profile... -
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