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The Function of 5-HT(1A) Receptor and Pharmacotherapy

Kim W, Bahk WM

  • KMID: 2287360
  • Korean J Psychopharmacol.
  • 2006 May;17(3):253-262.
5-HT(1A) receptor is implicated in the pathogenesis and the therapeutic mechanism of various psychiatric disorders. Especially, the mechanism of action of selective serotonin reuptake inhibitors (SSRIs) was hypothesized that 5-HT(1A)...
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Development History of Antipsychotic Drugs

Chung YI, Park SH

  • KMID: 2287363
  • Korean J Psychopharmacol.
  • 2006 May;17(3):283-290.
Discovery of antipsychotic drugs provided us with a turning point which was regarded as a revolutionary event in psychiatry. The pathophysiology of psychotic disorders such as schizophrenia had not been...
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Abnormal Laboratory Findings in Emergently Injected Psychiatric Inpatients: A Preliminary Report

Woo YS, Lee WH, Chae JH, Jun TY, Bahk WM

  • KMID: 2287365
  • Korean J Psychopharmacol.
  • 2006 May;17(3):302-306.
OBJECTIVE: Psychiatric patients often require emergency injection and they are sometimes received psychotropic medication injection before the completion of a medical history and laboratory studies. The aim of this study...
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Menstrual Resumption after Switching from Risperidone to Quetiapine Treatment: Case Series

Lee MS, Ko YH, Kim JW, Joe SH

  • KMID: 2287366
  • Korean J Psychopharmacol.
  • 2006 May;17(3):307-311.
INTRODUCTION: Hyperprolactinemia is associated with gonadal dysfunction, infertility and an increased risk of long-term complications including osteoporosis. METHODS: This is observational study investigating the effectiveness of a switching strategy using quetiapine...
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Serotonin Transporter and Pharmacotherapy

Kim SJ, Seok JH, Kim CH

  • KMID: 2287361
  • Korean J Psychopharmacol.
  • 2006 May;17(3):263-272.
The serotonin transporter (SERT) is the target site for serotonin reuptake inhibitors, which are the most widely used agents for treating various psychiatric diseases including depression. The SERT is a...
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Outlook of Future Serotonergic Drugs and Their Clinical Usefulness: Focused on Schizophrenia and Depression

Kim YK

  • KMID: 2287362
  • Korean J Psychopharmacol.
  • 2006 May;17(3):273-282.
Serotonin has been implicated in the etiology and pathophysiology of mental illness such as depression, schizophrenia, anxiety disorder, eating disorder, obsessive compulsive disorder, and panic disorder. Many current used treatments...
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Effects of Quetiapine on the Immobilization Stress-induced BDNF and CRF Expression in Rat Brain

Park SW, Lee SK, Kim YK, Lee SJ, Joo MJ, Rhee CG, Kim YH

  • KMID: 2287364
  • Korean J Psychopharmacol.
  • 2006 May;17(3):291-301.
OBJECTIVE: In this study we examined the effects of quetiapine on the immobilization stress-induced brain-derived neurotrophic factor (BDNF) and corticotropin-releasing factor (CRF) expression in rat brain. We also assessed the...
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