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5-HT(1A) receptor is implicated in the pathogenesis and the therapeutic mechanism of various psychiatric disorders. Especially, the mechanism of action of selective serotonin reuptake inhibitors (SSRIs) was hypothesized that 5-HT(1A)...
Discovery of antipsychotic drugs provided us with a turning point which was regarded as a revolutionary event in psychiatry. The pathophysiology of psychotic disorders such as schizophrenia had not been...
OBJECTIVE: Psychiatric patients often require emergency injection and they are sometimes received psychotropic medication injection before the completion of a medical history and laboratory studies. The aim of this study...
INTRODUCTION: Hyperprolactinemia is associated with gonadal dysfunction, infertility and an increased risk of long-term complications including osteoporosis.
METHODS: This is observational study investigating the effectiveness of a switching strategy using quetiapine...
The serotonin transporter (SERT) is the target site for serotonin reuptake inhibitors, which are the most widely used agents for treating various psychiatric diseases including depression. The SERT is a...
Serotonin has been implicated in the etiology and pathophysiology of mental illness such as depression, schizophrenia, anxiety disorder, eating disorder, obsessive compulsive disorder, and panic disorder. Many current used treatments...
Park SW, Lee SK, Kim YK, Lee SJ, Joo MJ, Rhee CG, Kim YH
KMID: 2287364
Korean J Psychopharmacol.
2006 May;17(3):291-301.
OBJECTIVE: In this study we examined the effects of quetiapine on the immobilization stress-induced brain-derived neurotrophic factor (BDNF) and corticotropin-releasing factor (CRF) expression in rat brain. We also assessed the...