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Next Generation DNA Sequencing and Its Application in Clinical Medicine

Cho S

Watson and Crick published a paper on the double helical structure of DNA in Nature in April 25, 1953. The human genome is contained in the 23 pairs of chromosomes...
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Multiple Intussusceptions in an Extremely Premature Infant

Kim HS, Kim HA, Kim SH, Byun SY, Kim MJ

Intussusception in premature infants is very rare. Here, we report a case of multiple intussusceptions in an extremely preterm infant, born at 23+1 weeks gestation, who underwent an explolaparotomy, for...
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A Case of Subcutaneous Fat Necrosis of the Newborn with Hypoglycemia and Meconium Aspiration Syndrome

Kim TH, Choi MS, Chung SH, Choi YS, Sim WY, Bae CW

Subcutaneous fat necrosis of the newborn is a rare, benign disease usually found in full-term infants. It occurs usually in a few weeks after birth, as one or multiple indurated...
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A Huge Umbilical Vein Aneurysm: Case Report and a Brief Review of Literatures Describing Umbilical Vessel Aneurysm

Lee JH, Cho JH, Kwon HY, Park YW, Kim YH

An umbilical vein aneurysm is rare, but appears to be associated with fetal morbidity and mortality. There are no specific guidelines for pregnancy with umbilical vein aneurysm and the management...
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Integrated Care Center for High Risk Pregnancy and Neonate: An Analysis of Process and Problems in Obstetrics

Kim HY, Moon CS

The medical environment of obstetric field has been deteriorated seriously, which is caused by sharply declined birth rates and several other causes in Korea. Inversely, the prevalence of high risk...
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Paroxysmal Supraventricular Tachycardia at 1-Month Age and Transient Thyroid Dysfunction in a Preterm Baby Treated for Fetal Tachycardia with Amiodarone

Nam SW, Ko SY, Lee YK, Yoon SY, Park SW, Shin SS

Fetal tachycardia is mostly benign, but sometimes results in serious consequences such as fetal hydrops and fetal death. To decrease cardiovascular burden, fetuses could be treated with transplacental administration of...
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A Case of Herpes Simplex Virus Type 2 Encephalitis of a Newborn Delivered by a Mother without Prenatal Screening

Lee ES, Kim JY, Lee KH, Lee JW, Lee YJ, Oh YJ, Bang JS, Sung TJ

Neonatal herpes simplex virus (HSV) encephalitis is a rare disease nowadays because of prenatal screening test and management. It shows progressive central nervous system manifestations affecting predominantly temporal and frontal...
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The Most Important Factors for Retinopathy of Prematurity in Preterm Infants

Choi JY, Han YI, Kim JH, Kim ES, Jeon J

PURPOSE: There are many known risk factors for a retinopathy of prematurity (ROP). We analyzed the most important risk factors and predictors of ROP among them. METHODS: We retrospectively reviewed the...
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Current Status and Availability of Specialized Maternity Non-Standard Room for Delivering Mothers

Yoon JW, Han SW, Lee SH, Jung YS, Kim JM, Kim EH

PURPOSE: Demand of specialized maternity ward is increasing as national income level rises. However, the National Health Insurance limits the number of hospital's non-standard room to less than 50% of...
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Effects of Dizocilpine (MK-801) via Up-modulation of N-methyl-D-aspartate (NMDA) Receptors on Hypoxic-Ischemic Brain Injury in Neonatal Rats

Kim JH, Lee HJ, Lee EJ, Choi EJ, Kim JK, Chung HL, Kim WT

OBJECTIVE: Several studies have demonstrated the neuroprotective effects of (+)-MK-801 hydrogen maleate (dizocilpine), in various animal models of hypoxic-ischemic (HI) brain injury. However limited data are available on the neonatal...
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