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Clinical application of gonadotropin-releasing hormone analogs in children and adolescents

Kim HS

Although the increasing incidence of central precocious puberty (CPP) in Korea has recently raised public concerns about health and growth problems, there are many areas of uncertainty regarding the pathogenesis,...
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The current child and adolescent health screening system: an assessment and proposal for an early and periodic check-up program

Eun BL, Moon JS, Eun SH, Lee HK, Shin SM, Sung IK, Chung HJ

PURPOSE: Recent changes in the population structure of Korea, such as rapid decline in birth rate and exponential increase in old-aged people, prompted us to prepare a new health improvement...
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Pediatric dual-energy X-ray absorptiometry: interpretation and clinical and research application

Lim JS

Peak bone mass is established predominately during childhood and adolescence. It is an important determinant of future resistance to osteoporosis and fractures to gain bone mass during growth. The issue...
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Comparison of clinical and laboratory characteristics in children with type 1 diabetes according to pancreatic autoantibodies

Choi JH, Kim MS, Kim CJ, Kim JD, Lee DY

PURPOSE: The purpose of this study was to determine whether there is any difference in the clinical and laboratory characteristics of patients with autoantibody-positive and patients with autoantibody-negative type 1...
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One-year evaluation of the national health screening program for infants and children in Korea

Moon JS, Lee SY, Eun BL, Kim SW, Kim YK, Shin SM, Lee HK, Chung HJ

PURPOSE: Results of the Korea National Health Screening Program for Infants and Children, which was launched in November 2007, were evaluated for future research and policy development. METHODS: Data from a...
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Effect of Synagis(R) (palivizumab) prophylaxis on readmission due to respiratory syncytial virus in very low birth weight infants

Park SK, Jung YJ, Yoo HS, Ahn SY, Seo HJ, Choi SH, Kim MJ, Jeon GW, Koo SH, Lee KH, Chang YS, Park WS

PURPOSE: The aim of this study was to determine the efficacy of Synagis(R) (palivizumab) in reducing the respiratory syncytial virus (RSV) readmission rate in very low birth weight infants (VLBWI...
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Predictable risk factors and clinical courses for prolonged transient tachypnea of the newborn

Chang JY, Kim CR, Kim EA, Kim KS

PURPOSE: Transient tachypnea of the newborn (TTN) is usually benign and improves within 72 hours. However, it can also progress to prolonged tachypnea over 72 hours, profound hypoxemia, respiratory failure,...
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Caregivers' adherence factors affecting maintenance treatment in children with well-controlled asthma : A qualitative analysis through in-depth interview

Choi IS, Cho SK, La KS, Byeon JH, Song DJ, Yoo Y, Choung JT

PURPOSE: Good adherence of caregivers is essential for successful health outcomes in the treatment of childhood asthma. The purpose of this study was to identify the factors contributing to good...
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A case of steroid-induced psychosis in a child having nephrotic syndrome with toxic epidermal necrolysis

Kim SY, Lee JM, Park YH

Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are rare, life-threatening mucocutaneous diseases, usually attributable to drugs and infections. Corticosteroids have been used in the management of TEN for the...
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Spectrum of patients with hypermethioninemia based on neonatal screening tests over 14 years

Oh SJ, Hong YH, Lee YW, Lee DH

PURPOSE: The neonatal screening test for homocystinuria primarily measures methionine by using a dried blood specimen. We investigated the incidence and clinical manifestations of homocystinuria, isolated hypermethioninemia, and transient hypermethioninemia...
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Body composition by bioelectrical impedance analysis in children below 7 years old

Jung J, Kim HW, Kim TH, Hong YM

PURPOSE: Body composition is important to define and manage obesity and undernutrition. Obesity is a significant health problem with medical and psychological consequences for children and adolescents. Body composition analysis...
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Thrombotic thrombocytopenic purpura with decreased level of ADAMTS-13 activity and increased level of ADAMTS-13 inhibitor in an adolescent

Yang EM, Han DK, Baek HJ, Shin MG, Kim YO, Kook H, Hwang TJ

Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy characterized by endothelial cell damage, resulting in microangiopathic hemolytic anemia, thrombocytopenia, and various degrees of neurological and renal impairment caused by microvascular...
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Respiratory syncytial virus infection cases in congenital heart disease patients

Shim WS, Lee JY, Song JY, Kim SJ, Kim SH, Jang SI, Choi EY

PURPOSE: Respiratory syncytial virus (RSV) is one of the main pathogens causing lower respiratory infections (LRI) in young children, usually of limited severity. However, in congenital heart disease (CHD) patients,...
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Relationship between iron deficiency anemia and febrile convulsion in infants

Jun YS, Bang HI, Yu ST, Shin SR, Choi DY

PURPOSE: The association between iron deficiency anemia and febrile convulsion in infants has been examined in several studies with conflicting results. Therefore, the authors aimed to evaluate the precise relationship...
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Direct detection of hemophilia B F9 gene mutation using multiplex PCR and conformation sensitive gel electrophoresis

Yoo KY, Kim HJ, Lee KC

PURPOSE: The F9 gene is known to be the causative gene for hemophilia B, but unfortunately the detection rate for restriction fragment length polymorphism-based linkage analysis is only 55.6%. Direct...
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Genetic testing in clinical pediatric practice

Yoo HW

Completion of the human genome project has allowed a deeper understanding of molecular pathophysiology and has provided invaluable genomic information for the diagnosis of genetic disorders. Advent of new technologies...
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Effect of hyperglycemia on mortality rates in critically ill children

Kim S, Kim BE, Ha EJ, Moon MY, Park SJ

PURPOSE: To verify the effect of hyperglycemia on mortality rates in critically ill children and to identify the blood glucose level that influences prognosis. METHODS: From July 2006 to June 2008,...
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Transient neonatal diabetes mellitus with macroglossia diagnosed by methylation specific PCR (MS-PCR)

Jin HY, Choi JH, Kim GH, Yoo HW

Transient neonatal diabetes mellitus (TNDM) has been associated with paternal uniparental isodisomy of chromosome 6, paternally inherited duplication of 6q24, or a methylation defect at a CpG island of the...
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Effects of a 12-week, school-based obesity management program on obese primary school children

Kim HG, Lim GW, Kim HS, Hong YM

PURPOSE: This study was designed to determine the effects of a school-based obesity-management program on obese primary school children. METHODS: A total of 995 children (6-12 years old) in a primary...
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Limitations of 99mTc-DMSA scan in diagnosing acute pyelonephritis in children

Kim BG, Kwak JR, Park JM, Pai KS

PURPOSE: We aimed to prove the relative limitation of 99mTc-DMSA scintigraphy (DMSA) compared to computed tomography (CT) in diagnosing acute pyelonephritis (APN) in children. METHODS: Since September 2006, after a 64-channel...
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