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Hemolytic anemia in pediatrics

Hah JO

To understand the hemolytic anemia (HA) in children, the diagnostic approach and management of hereditary and acquired HA are described. The hereditary hemolytic anemia (HHA) can be classified according to...
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A case of childhood relapsing/remitting multiple sclerosis and interferon beta-1b treatment in a Korean patient

Kim HS, Lee WD, Lee JH, Cho KL

Multiple sclerosis (MS) is a demyelinating disorder that affects discrete areas of the CNS, including the optic nerves, in a quite variable relapsing-remitting fashion over a prolonged period of time....
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A case of neonatal peroneal neuropathy with intrauterine onset

Lee SS, Sim JY, Kim MJ

Peroneal neuropathy presenting at birth is a rare disorder. Although neonatal mononeuropathies may be related to obstetrical complications, prenatal mechanisms should be also considered. We describe an infant who was...
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Polymorphism in the promoter region of the plasminogen activator inhibitor-1 (PAI-1) gene in Kawasaki disease

Han MY

PURPOSE: To demonstrate genetic background of pathogenesis of Kawasaki disease (KD), I examined the genetic polymorphism of plasminogen activator inhibitor-1 (PAI-1) in KD patients. METHODS: PCR-RFLP of PAI- 1 promotor...
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Recent advances in histiocytic disorders

Seo JJ

The recent advances in the basic hematology and immunology have significantly enhanced the understanding of histiocytic disorders. The Histiocyte Society which was established in 1985 enabled the randomized trials for...
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The factors associated with the efficacy of indomethacin treatment in premature infants with patent ductus arteriosus

Yoon MJ, Yoon HS, Hoon CS, Han MY, Bae CW

PURPOSE: Indomethacin treatment is successful in about 90% of patent ductus arteriosus (PDA) in premature infants, but in some, repeated administration or surgical closure is required. The object of the...
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Pulse wave velocity and ankle brachial index in normal adolescents

Kim JH, Gil TY, Lee HW, Hong YM

PURPOSE: Pulse wave velocity (PWV) and ankle brachial index (ABI) are simple, non-invasive methods to assess arterial stiffness. These parameters are also known to be closely related to cardiovascular risk...
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Identification of a de novo mutation (H435Y) in the THRB gene in a Korean patient with resistance to thyroid hormone

Shin JY, Ki CS, Kim JK

The syndrome of resistance to thyroid hormone (RTH) is characterized by reduced tissue sensitivity to thyroid hormone (TH). In the majority of subjects, RTH is caused by mutations in the...
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Analysis of the association between bronchial hyperresponsiveness and genetic polymorphism of beta2-adrenoceptor in adolescents with long-term asthma remission

Kang H, Koh YY

PURPOSE: We hypothesized that the persisting bronchial hyperresponsiveness (BHR) of adolescents with asthma remission may be controlled mainly by genetic factors, and the BHR of symptomatic asthma by airway inflammation....
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The effect of Lantus on glycemic control in children and adolescents with type 1 diabetes mellitus

Rhie YJ, Chae HW, Kim HS, Kim DH

PURPOSE: With a duration of action of approximately 24 hours and peakless levels, Lantus is a more physiologic basal insulin analogue compared with NPH. The aim of this study was...
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Surgical removal of a left ventricular thrombus caused by acute myocarditis

Lee KH, Yoon MJ, Han MY, Chung SJ, Kim SC

Left ventricular thrombus is mainly caused by anterior myocardial infarction or severe cardiac wall dysfunction of the apex, and is rarely caused by a complication of acute myocarditis. A 12-year-old...
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Aplastic anemia

Kim HK

Aplastic anemia is a rare disease, which is characterized by pancytopenia and hypocellular bone marrow without infiltration of abnormal cells or fibrosis. The incidence in Asia is higher than in...
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The effect of restricted fluid intakes in the first week of life on the risk of bronchopulmonary dysplasia and patent ductus arteriosus in very low birth weight infants

Koo HK, Choi EN, Namgung R, Park MS, Park KI, Lee C

PURPOSE: We investigated the effects of restricted fluid in the first 7 days of life on the risk of bronchopulmonary dysplasia (BPD) or patent ductus arteriosus (PDA) in very low...
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Analysis of anthropometric data for premature infants of 26 to 35 weeks of gestation; comparison with the data of 1960's

Aum JA, Jung HJ, Huh JW, Son SH

PURPOSE: The anthropometric data of newborns published by Lubchenco et al in the 1960's have been most commonly used in Korea as a standard of newborn growth. We hypothesized that...
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