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Two Cases of Megaloblastic Anemia Induced by Vitamin B12 Deficiency in Children

Kim JY, Kim BM, Lee KS

  • KMID: 2037396
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):97-101.
Megaloblastic anemia induced by Vitamin B12 deficiency is a disorder caused by impaired DNA synthesis. It has been previously thought to be rare in children, however, recent studies suggest that...
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Defibrotide Treatment for Hepatic Veno-occlusive Disease after Umbilical Cord Blood Transplantation

Yi JS, Kook H, Noh HY, Baek HJ, Kim SY, Sohn KR, Choi IS, Park HJ, Hwang TJ

  • KMID: 2037395
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):92-96.
Veno-occlusive disease (VOD) of the liver is a life-threatening complication occurring early after blood or bone marrow transplantation (BMT). Effective treatment has not been established in case of severe forms...
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Secondary Renal Cell Carcinoma in a Child Treated for Germ Cell Tumor

Nam CH, Lee HS, Choi SR, Chung SY, Kang JH, Suh HJ, Kim KM, Jeong DC, Kim HK

  • KMID: 2037394
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):86-91.
Advances for the treatment of childhood cancer in several decades have remarkably improved long-term survival. Anticancer therapy is capable of causing a variety of delayed toxicities including secondary malignant neoplasm....
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Hepatic Veno-occlusive Disease after Combination Chemotherapy with Vincristine, Actinomycin-D, Cyclophosphamide: Successful Treatment with Glutathione and Vitamin E

Lee KH, Bae H, Park HJ

  • KMID: 2037393
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):80-85.
Hepatic veno-occlusive disease (VOD) is characterized by the narrowing or fibrous obliteration of terminal hepatic venules and small sublobular veins. The obliteration of blood flow may lead to tender hepatomegaly,...
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Isolated Thymic Langerhans Cell Histiocytosis

Jung YH, Hwang SU, Park JK, Oh MY, Lee SY

  • KMID: 2037392
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):74-79.
Langerhans cell histiocytosis is a rare disease in which the Langerhans cells proliferate abnormally, like a cancer, and involve various tissues and organs, such as skin, bone, lung, lymph node,...
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Isolated Extramedullary Relapse of Acute Lymphoblastic Leukemia Presenting as an Paraspinal Mass

Kim JY, Kim HR, Woo CO, Lee JH, Chung UY, Lee KC

  • KMID: 2037391
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):68-73.
Despite improvements in therapy, cases in which relapse occurs are still common in children with acute lymphoblastic leukemia (ALL). Most relapses occur in the bone marrow, and extramedullary relapse is...
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A Case of Desmoplastic Small Round Cell Tumor

Cho YB, Ahn HS, Shin HY, Choi HS, Park ES, Kim CJ

  • KMID: 2037390
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):62-67.
Desmoplastic small round cell tumor (DSRCT) is a distinct clinicopathologic entity that has only recently been described. This aggressive malignant small cell neoplasm tends to occur in adolescents and young...
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Granulocytic Sarcoma in Childhood Acute Myelogenous Leukemia: Clinical Characteristics and Management

Oh CK, Kook H, Kim SJ, Noh HY, Sohn KR, Baek HJ, Hwang TJ

  • KMID: 2037389
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):55-61.
PURPOSE: Granulocytic sarcoma (GS), an extramedullary tumor consisting of primitive myeloid cells, is a rare manifestation of acute myelogenous leukemia (AML). However, GS can occasionally precede the development of systemic...
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Clinical Characteristics and Treatment Outcome of Childhood Langerhans Cell Histiocytosis

Noh HY, Sohn KR, Baik HJ, Kim SJ, Nam HS, Kook H, Hwang TJ

  • KMID: 2037388
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):45-54.
PURPOSE: We analyzed a cohort of patients with Langerhans cell histiocytosis (LCH) to understand the clinical findings, optimal management, and outcome of the disease. METHODS: We performed a retrospective clinical...
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Treatment of Children with Anagrelide for Essential Thrombocythemia

Kim JY, Lee KS

  • KMID: 2037387
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):39-44.
PURPOSE: Essential thrombocythemia (ET) in children is a rare myeloproliferative disease characterized by persistent elevation of platelets and is associated with an increased risk of thrombohemorrhagic complications. For patients with...
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Factors Related to the Thrombocytosis in Children with Iron Deficiency Anemia

Keun SO, Lee SM, Chung SY, Kang JH, Jeong DC

  • KMID: 2037386
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):32-38.
PURPOSE: We investigated to identify factors related to thrombocytosis and clinical data for thrombopoiesis in children with iron deficiency anemia (IDA). METHODS: We retrospectively analyzed clinical and laboratory data for...
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Treatment of Chronic Idiopathic Thrombocytopenic Purpura in Children with Cepharanthin (R)

Han HJ, Lee IS, Shin HY, Park ES, Choi HS, Ahn HS

  • KMID: 2037385
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):26-31.
PURPOSE: Cepharanthin (R) has been reported to improve the symptoms of intractable or steroid-resistant chronic idiopathic thrombocytopenic purpura (ITP). We report the clinical efficacy of oral high dose Cepharanthin (R)...
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Distribution and Characteristics of CD133+, CD34+ Cells in Counterflow Centrifugal Elutriation Fraction of Cord Blood and Bone Marrow

Park HJ, Chung NG, Kim SY, Jeong DC, Jang PS, Cho B, Kim HK

  • KMID: 2037384
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):17-25.
PURPOSE: Many studies for hematopoietic stem cell have investigated CD133, instead of CD34, as a new surrogate stem cell marker. Counterflow centrifugal elutriation (CCE) is a physical separation of a...
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The Effect of Stromal Cells and Hematopoietic Growth Factors on Proliferation and Differentiation of Megakaryocytic Progenitors from Umbilical Cord Blood

Choi HS, Koh SH, Park ES, Shin HY, Ahn HS

  • KMID: 2037383
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):7-16.
PURPOSE: CD34+ cells from umbilical cord blood (UCB) were cultured with stromal cells and growth factors, and cell proliferation and megakaryocytic differentiation were observed. The purposes of this study are...
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Change of Platelet Count and Mean Platelet Volume after Intravenous Immunoglobulin Injection in Acute Idiopathic Thrombocytopenic Purpura

Jeon IS, Kim JS, Im HJ

  • KMID: 2037382
  • Korean J Pediatr Hematol Oncol.
  • 2004 Apr;11(1):1-6.
PURPOSE: The platelet synthesis is extremely variable after intravenous immunoglogulin injection (IVIG) in acute idiopathic thrombocytopenic purpura (ITP). To investigate the size variation of platelet according to the time sequence...
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