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A Study of Neurological Soft Signs in Patients with Schizophrenia and Their Unaffected Siblings

Cho JW, Kim SH, Lee YS

OBJECTIVES: This study was conducted to investigate the possibility of neurological soft signs as an endophenotype for schizophrenia by examining neurological soft signs in patients, their unaffected siblings and normal...
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Evolutionary Meaning of Sadness, Depression, and Suicide

Shin CJ

Depression has a relatively high lifetime prevalence rate in spite of a genetic influence on its etiology and a high mortality rate in untreated cases. This suggests the possibility that...
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The Effect of Circadian Types and Depressive Mood on Internet Addiction in Korean College Students

Oh KS, Lee HK, Lee K

OBJECTIVES: The purpose of this study was to investigate the relationships among circadian types, depressive mood and internet addiction and to identify the mediating effect of depressive mood between circadian...
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Menopause and Cognitive Function : Hospitalized Female Patients with Depression

You JY, Min JA, Jeon YW, Han SI, Park EJ

OBJECTIVES: Although forgetfulness is a common complaint among menopausal depressed women, there is still a debate about the relationship between memory impairment and menopause. The aim of this study is...
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Association between COMT and 5-HTTLPR Polymorphisms in Korean Patients with Panic Disorder : A Replication Study

Kim SW, Choi TK, Lee SH

OBJECTIVES: We investigated whether the catechol-O-methyltransferase (COMT) and serotonin related gene polymorphisms may be associated with agoraphobia in patients with panic disorder in Korea. METHODS: The COMT gene (rs4680), 5-hydroxytryptamine (serotonin)...
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Clinical Characteristics of Female Panic Disorder with Early Sexual Abuse History

Kim KM, Kim MK, Lee KS, Choi TK, Lee SH

OBJECTIVES: The objective of this study is to investigate differences of clinical characteristics between a healthy female control group and female panic disorder (PD) patients with early sexual abuse history...
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Correlation between Quantitative Electroencephalogram Findings and Neurocognitive Functions in Patients with Obsessive-Compulsive Disorder and Schizophrenia

Kim S, Shin JE, Kim MJ, Kwon JS, Choi SH

OBJECTIVES: Obsessive-compulsive disorder (OCD) and schizophrenia have many common clinical and neurocognitive features. However, not all of them share the same underlying mechanism. The aim of this study was to...
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Long-Term Treatment Response to Lithium and Valproate in Patients with Bipolar 1 Disorder Treated More Than 2 Years : A Retrospective Study

Ahn SW, Yang SY, Choi Y, Hong KS

OBJECTIVES: Treatment response of bipolar disorders (BDs) to long-term mood stabilizers maintenance has not been well explored because of complicated clinical and treatment courses. This study aims at investigating long-term...
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Association between the Alu Insertion/Deletion Polymorphism in the Tissue-Type Plasminogen Activator Gene and Mirtazapine Response in Koreans with Major Depression

Kim D, Chang HS, Won E, Ham BJ, Lee MS

OBJECTIVES: To determine the relationship between the Alu insertion/deletion (I/D) polymorphism in the tissue-type plasminogen activator (tPA) gene and the clinical outcome of mirtazapine treatment in Korean major depressive disorder...
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A Comparative Study of Permissive Attitudes Toward Suicide : An Analysis of Cross-National Survey in South Korea, Japan, and the United States

Park CH, Kim B, Lee SS, Ha K, Baek CJ, Shin MS, Ahn YM

OBJECTIVES: There were previous studies which indicated that attitude toward suicide is able to influence the suicide outcome in both individual and group levels. In regard to the highest suicide...
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No Association between (AAT)n Repeat Polymorphisms in the Cannabinoid Receptor 1 Gene and Smooth Pursuit Eye Movement Abnormality in Korean Patients with Schizophrenia

Kim MJ, Kim CR, Park JW, Pak DH, Shin HD, Choi IG, Hahn SW, Hwang J, Lee YJ, Woo SI

OBJECTIVES: According to previous studies, the cannabinoid receptor 1 (CNR1) gene could be an important candidate gene for schizophrenia. Some studies have linked the (AAT)n trinucleotide repeat polymorphism in CNR1...
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