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Spontaneous Coronary Artery Dissection Manifested during Ergonovine Test and Treated with Intravascular Ultrasound Guided Stenting: A Case Report

Ahn SG, Tahk SJ, Choi JH, Yoo SY, Zheng ZG, Choi BJ, Choi TY, Choi SY, Yoon MH, Hwang GS, Shin JH

Spontaneous coronary artery dissection (SCAD) is an uncommon cause of acute myocardial ischemia, which frequently presents as sudden death. The pathophysiology and treatment of SCAD have not been fully determined....
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Heritability and Segregation Analysis of the Level of LDL-Cholesterol

Jee SH, Yun JE, Nam CM, Suh I

BACKGROUND AND OBJECTIVES: The purpose of this study was to investigate the familial correlation and heritability of the LDL cholesterol level through a segregation analysis. SUBJECTS AND METHODS: This study...
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The Clinical Usefulness of Decreased Mean Platelet Component Concentration in Patients with Acute Coronary Syndrome

Kim KY, Bae JH

BACKGROUND AND OBJECTIVES: The reduction in the mean platelet component (MPC) concentration may be used to detect platelet activation. We performed this study to find the clinical usefulness of the...
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New Drug-Eluting Stents

Hong YJ, Jeong MH

The introduction of drug-eluting stents (DES) has rapidly and profoundly affected the field of interventional cardiology, and DESs are now used in a majority of intracoronary stenting procedures. As a...
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Clinical Values of the Posterior Chest Leads for Patients with Myocardial Infarction

Kim KH, Cho JG, Yun KH, Hong YJ, Park HW, Kim JH, Kim W, Ahn YK, Jeong MH, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: The standard 12 lead electrocardiography (ECG) is very valuable in the evaluation of myocardial infarction (MI), but it has many limitations for the diagnosis of posterior wall...
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An Insertion/Deletion Polymorphism in the alpha(2B)-Adrenoceptor Gene is not a Genetic Risk Factor for Coronary Artery Disease in the Korean Population

Choi JR, Park CM, Hong JA, Bae SJ, Eom SM, Cho EY, Ko YG, Park HY, Jang YS

BACKGROUND AND OBJECTIVES: Cardiovascular disease (CVD) is a complex multigenic disorder, with significant inheritable elements having important roles relating to environmental factors. Recently, the alpha 2 adrenoceptor (alpha(2)-AR) gene has...
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Efficacy and Safety of Amlodipine Camsylate(Amodipin(TM)) for Treatment of Essential Hypertension

Shin EK, Chung WS, Seo HS, Yang JY, Park JB, Kim JJ, On YK

BACKGROUND AND OBJECTIVES: Amlodipine camsylate (Amodipin(TM)), a newly developed amlodipine formulation, has similar physical properties and pharmacokinetic equivalency to that of the conventional formulation (amlodipine besylate, Norvasc(R)). SUBJECTS AND METHODS:...
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Feasibility of Transradial Coronary Angiography Using a Single Judkins Left Catheter

Park EH, Kim MH, Park TH, Ahn SJ, Jung DS, Paik JH, Cha KS, Kim YD, Kim JS

BACKGROUND AND OBJECTIVES: Transradial coronary angiography and intervention are getting more popularity throughout the world because of lower incidence of puncture site complications and the patients have displayed early ambulation....
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Relationship between Heart Rate Reduction and Insulin Resistance in Normoglycemic Individuals

Seo HI, Sung KC, Shin HS, Hwang SJ, Park SK, Kim BJ, Kim BS, Kang JH, Lee MH, Park JR, Rhee EJ, Lee WY, Kim SW, Keum DG

BACKGROUND AND OBJECTIVES: It is well known that, regardless of whether a person has cardiovascular diseases, the reduction of heart rate after exercise reflects the impairment of the autonomic nervous...
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Perivascular Delivery of Paclitaxel with F-127 Pluronic Gel Inhibits Neointimal Hyperplasia in a Rat Carotid Artery Injury Model

Kwon JS, Park SS, Kim YG, Son JH, Lee YS, Kim KS, Hwang KK, Kim DW, Cho MC

BACKGROUND AND OBJECTIVES: The local delivery of drugs to the arterial wall represents a strategy for the treatment of fibroproliferative vascular disease. Paclitaxel has been shown to inhibit vascular smooth...
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in vivo Cardiac Gene Transfer of Dominant Negative IKK-beta Reduces Myocardial Inflammation, Apoptosis, and Infarction after Ischemia-Reperfusion Injury

Ahn YK, Kim YS, Park HW, Hong YJ, Kim JH, Kim W, Jeong MH, Cho JG, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: NF-kappaB transcription factors drive the expressions of many genes involved in inflammation and cell survival, which are both important in ischemia-reperfusion (IR) injury. IKK-beta can mediate NF-kappaB...
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