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A Case of Hereditary Hemorrhagic Telangiectasia Combined with Pulmonary- Systemic Fistula

Chang SA, Oh S, Koo JM, Kim HK, Cho HJ, Park SR, Lee MM, Park YB, Choi YS

We report the first case of hereditary hemorrhagic telangiectasia combined with multiple pulmonary-systemic fistulae. In this case, a 39-year-old woman presented with long standing chest pain, dyspnea and hemoptysis. Finally...
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A Family with A Missense Mutation in the SCN5A Gene

Shin CH, Kim NH, Kim KH, Yoo SS, Choi YB, Oh SK, Hong KM, Jeong JW, Paik MK

Brugada syndrome, an autosomal dominantly inherited form of ventricular fibrillation, is characterized by ST-segment elevation in leads V1-3 and right bundle-branch block on surface electrocardiogram. It is caused by mutations...
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A Case of Emery-Dreifuss Muscular Dystrophy by Emerin Gene Mutation

Kim SE, Hong JS, Ahn KJ, Kim JS, Kim DK

Emery-Dreifuss muscular dystrophy (EDMD) is a degenerative myopathy characterized by mild, slowly progressing weakness, muscle atrophy, and early contracture of the neck, ankle and elbow. Heart involvement becomes apparent during...
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Value of ST-segment Elevation Pattern in Predicting Left Ventricular Function in Patients with Reperfused Acute Anterior Myocardial Infarction

Kim NH, Jeong JW, Oh SK, Ahn YK, Jeong MH, Cho JG, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: The implication of the shape of ST elevation in the acute phase of myocardial infarction (MI) remains unclear. SUBJECTS AND METHODS: We examined the relationship between the shape...
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Sex Differences in Early Management of Patients with Acute Myocardial Infarction (AMI) in the 1990s

Moon KW, Lee MY, Chung WS, Kim CJ, Seung KB, Jeon DS, Kim HY, Jin SW, Ihm SH, Kim PJ, Park IS, Kim JH, Choi KB, Hong SJ

BACKGROUND AND OBJECTIVES: Previous studies have suggested that women with AMI are less aggressively managed than men. The aim of this study was to assess the differences between the sexes,...
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The Relationship between Preceding RR Intervals and Peak Ejection Velocity of Left Ventricular Outflow in Atrial Fibrillation without Organic Heart Diseases

Cho SW, Kim SM, Lee SY, Ahn JH, Song YB, Lee KJ, Kim SW, Kim TH, Ko HS, Kim CJ, Ryu WS

BACKGROUND AND OBJECTIVES: Cardiac performance is dependent on both the preceding RR interval (RR-1) and the prepreceding RR interval (RR-2) in atrial fibrillation (AF). We reported a new method for...
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Relationship of Polymorphisms in the Oxidative Stress Related Genes - Paraoxonase and p22phox - to Variant Angina and Coronary Artery Stenosis in Korean

Cho YS, Choi JH, Zhang SY, Lee JH, Hwang KK, Kim HS, Oh BH, Lee MM, Park YB, Choi YS

BACKGROUND AND OBJECTIVES: Oxidative stress plays an important role in the pathogenesis of coronary atherosclerosis and spasm. We investigated whether the polymorphisms in two oxidative stress-related genes, paraoxonase and p22phox,...
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Early Diagnosis of Acute Coronary Syndrome Using Myocardial Contrast Echocardiography

Kang DH, Kang SJ, Kim YH, Hwang ES, Song JM, Choi KJ, Hong MK, Song JK, Park SW, Park SJ, Kim YH

BACKGROUND AND OBJECTIVES: Without typical electrocardiographic (ECG) changes, and the elevation of cardiac enzymes, the early identification of high risk chest pain patients remains a major challenge. We hypothesized that...
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Age and Gender Distribution of Patients with Acute Myocardial Infarction Admitted to University Hospitals during the Period of 1990-1999

Moon HK, Kim YD, Yang DG, Kim SG, Cha KS, Kim MH, Kim JS, Cha TJ, Joo SJ, Lee JW, Hong TJ, Shin YW, Kim DI, Kim DS, Park JS, Shin DG, Kim YJ

BACKGROUND AND OBJECTIVES: The prevalence of coronary disease in Korea, with the consequent morbidity and mortality, has rapidly risen during the last two decades. This study aimed to describe the...
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Effect of Angiotensin II on Gene Expression of cGMP-Specific Phosphodiesterases

Kim D, Hong BK, Kwon HM, Kim DY, Cho YH, Yoon SJ, Kim HS, Yan C

BACKGROUND AND OBJECTIVES: Angiotensin II (Ang II) opposes the actions of nitric oxide (NO). A balance between Ang II and NO is critical for the maintenance of normal vessel tone,...
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The Role of Extracellular Matrix within the Neointima in A Porcine Coronary Stent Restenosis Model

Park OY, Jeong MH, Kim JH, Kim W, Lee SH, Hong YJ, Kim JH, Park WS, Ahn YK, Park JT, Cho JG, Park JC, Kang JC

BACKGROUND AND OBJECTIVES: Coronary stent restenosis remains a major limitation to percutaneous coronary intervention. The most important mechanism of coronary stent restenosis is neointimal hyperplasia (NIH). In addition to neointimal...
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