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Patterns of Left Ventricular Hypertrophy by Echocardiography in Coronary Artery Diseases

Oh JY, Shin GJ, Park SH, Lee WH

BACKGROUND: Left ventricular hypertrophy is an independent risk factor for coronary artery disease, hypertension or other cardiovasular diseases, and normal health person due to cardiac arrhythmia or coronary microcirculatory insufficiency....
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A Case of Noonan Syndrome Combined with Infundibular Pulmonic Stenosis

Moon KW, Park JH, Yoo KD, Park JW, Youn HJ, Chung WS, Kim JH, Choi GB, Hong SJ, Lee SH, Kwak MS

The Noonan syndrome is a rate clinical syndrome associated with similar congenital abnormalities, that is characteristics of Turner syndrome, such as short stature, webbed neck, low posterior hairline, cubitus valgus,...
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A Clinical Study on Antihypertensive Effects and Safety of Benidipine

Hur SC, Chun DS, Lee KH, Cha H

BACKGROUND: This study was designed to evaluate the antihypertensive efficacy and safety of benidipine hydrochloride, a Ca(++)-channel blocker, in patients with mild to moderate essential hypertension. METHODS: Benidipine was administered in...
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Coronary Intervention of Cardiogenic Shock in Acute Myocardial Infarction

Choi JW, Song CS, Imm CW, Ahn TH, Choi IS, Shin IK, Park YH

BACKGROUND: Despite improvement of mortality in acute myocardial infarcrtion, high mortality rate associated with cardiogenic shock remains essentially unchanged. We have reviewed our result of coronary intervention in 15 patients...
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Evaluation of the Left Atrial Size and Function in Addition to Analysis of the Mitral and Pulmonary Venous Flow Velocity in the Estimation of Left Ventricular Filling Pressures

Lee HS, Bak NK, Kim DS, Chin YJ, Park GT, Kim DW, Cho MC

BACKGROUND: Mitral and pulmonary venous(PV) flow velocity variables are being used for the indirect evaluation of left ventricular(LV) diastolic function. However, these flow velocities are influenced by age, loading conditions...
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Concomitant Risk Factor of Atherosclerosis in Hypertensive Subjects

Cheigh YH, Chae SC, Jun JE, Park WH

BACKGROUND: Much of the recent understanding of hypertensive has focused on the importance of concomitant atherosclerotic risk factors in addition to the blood pressure itself and has created new therapeutic...
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CETP(Cholesteryl Ester Transfer Protein) Deficiency Caused by Genetic Mutation in the CETP Gene in Normal Korean Population

Han KH, Park YB, Chae IH, Kim HS, Sohn DW, Oh BH, Lee MM, Choi YS, Seo JD, Lee YW, Inazu A, Mabuchi H

BACKGROUND: CETP(Cholesteryl ester transfer Protein) is the essential protein for 'reverse cholesterol transport' which transfers cholesteryl ester from HDL particles to other lipoproteins. The subjects with CETP deficiency caused by...
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Two Cases of Torsade de Pointes after Astemizole Overdose

Kim SK, Jeon JW, Kim CH, Lee SW, Choi TM, Kwon YJ

A 52-year-old women, suffering from generalized pruritus due to intrahepatic and common hepatic duct stones, was treated with astemizole, 30mg daily. Sixty one days later, convulsions and syncope developed suddenly...
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Radiofrequency Catheter Ablation of Ventricular Tachycardia in Patients without Structural Heart Disease

Lee HJ, Choe CW, Kang HS, Kim KS, Kim MS, Song JS, Bae JH

BACKGROUND: Radiofrequency catheter ablation therapy of idiopathic ventricular tachycardia in patients without obvious structural heart disease has been assessed in a few studies, but the clinical feasibility and efficacy are...
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Lipoprotein(a) as a Risk Factor for Coronary Heart Disease : Whether Related with NIDDM or Not

Park SH, Shin GJ

BACKGROUND: It is now well established that hypercholesterolemia is an important cause of coronary heart disease, and clinical intervention studies have demonstrated the therapeutic value of correcting hypercholesterolemia. One of...
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Role of Prostaglandins on the Renin-Angiotensin System in Normotensive and Hypertensive Rats

Yoon PJ, Jung M, Kim JS, Jun JY, Yeum CH

BACKGROUND: Prostaglandin system is known to participate in manifestation of the renin-angiotensin system. However, role of prostaglandins on the renin-angiotensin system in development of hypertension is not well established. This...
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An I/D Polymorphism in Angiotensin-Converting Enzyme Gene in Myocardial Infarction

Park HY, Kwon HM, Kim HS, Song KS, Kim CH

BACKGROUND: The angiotensin-converting enzyme(ACE) plays an important role in cardiovascular disease by production of angiotensin and degradation of bradykinin. Cloning of ACE gene revealed an insertion/deletion(I/D) polymorphism according to the...
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Changes in Cytosolic Ca2+ Concentration of Single Rabbit Coronary Artery Smooth Muscle Cell during Ischemic Cardioplegic Period

Lee YH, Choi GB, Kim ST, Kang BS

BACKGROUND: No-reflow is a specific type of vascular damage occuring when removal of coronary occlusion dose not lead to restoration of coronary flow. There are three major explanations for the...
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Two-Dimensional Echocardiographic Predictors of Ventricular Enlargement after Acute Myocardial Infarction

Kim CM, Kim SR, Youn HJ, Lee MY, Choi KB, Hong SJ

BACKGROUND: Ventricular remodeling after myocardial infarction increase mortality and morbidity. Two-dimensional echocardiography in acute myocardial infarction provides a useful diagnostic tool for evaluation of ventricular remodeling. The aims of this...
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Clinical Findings of Aortic Dissection

Lee JY, Yoo BS, Ahan SC, Hwang SO, Yoon JH, Park KS, Choe KH

BACKGROUND: The purpose of this study is to evalute the clinical findings, DeBakey classification, major associated complication, and mortality of aortic dissection. METHOD: A retrospective clinical study was done on 43...
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Endothelial Dysfunction in Patients with Essential Hypertension

Doo YC, Rim CY, Lee JM, Koh SH, Han KR, Oh DJ, Ryu KH, Koh YB, Lee Y

BACKGROUND: The endothelium is an important regulator of vascular tone via release of relaxing and constricting substances. The regulatory effect of the endothelium has been shown to be impaired in...
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Ischemic Preconditioning in Isolated Rabbit Heart : Effect on Left Ventricular Function, Infarct Size, and Protein Kinase C*

Yoo HJ, Park JS, Kim H, Ryoo UH, Rah BJ, Kim HD

BACKGROUND: It has been demonstrated that ischemic preconditioning(IP, repetitive brief period of ischemia and reperfusion) enhances recovery of post-ischemic contractile dysfunction and reduces incidences of reperfusion-arrhythmia and infarct size after...
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Evaluation of Coronary Flow Reserve by Transesophageal Doppler Echocardiography in Patients with Chest Pain and Normal Coronary Angiogram

Youn HJ, Chung WS, Kim JJ, Park JC, Kim CM, Chae JS, Park IS, Kim JH, Choi KB, Hong SJ

BACKGROUND: The measurement of coronary flow reserve(CFR) is essential for assessing the flow capacity in patients with angina and normal coronary angiogram. Transesophageal Doppler echocardiography(TEE) is a noninvasive method of...
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Relation between QT Dispersion and Late Potential in Acute Myocardial Infarction

Lim DS, Kim YH, Lee SC, Park CG, Seo HS, Shim WJ, Oh DJ, Ro YM

BACKGROUND: QT dispersion(QTD=QTmax-QTmin) on the 12 lead ECG has been known to reflect regional variation of ventricular repolarization, and thus a marker of an increased risk of arrhythmia events. Late...
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The Effect of Reperfusion after Brief, Reversible Myocardial Ischemia on Coronary Vascular Function and Ultrastructure

Kim YH

BACKGROUND: Reperfusion after brief periods within 20 minutes of myocardial ischemia can result in prolonged depression of contractile function without causing myocardial necrosis-myocardial stunning. It has been also demonstrated that...
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