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The crosstalk between insulin resistance and nonalcoholic fatty liver disease/metabolic dysfunction-associated fatty liver disease: a culprit or a consequence?

Koo DJ, Lee WY

Nonalcoholic fatty liver disease (NAFLD), which has recently undergone a change in its definition and acronym to “metabolic dysfunction associated fatty liver disease (MAFLD),” is clinically significant as an increasingly...
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Insulin Resistance, Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Clinical and Experimental Perspective

Jung I, Koo DJ, Lee WY

It has been generally accepted that insulin resistance (IR) and reduced insulin secretory capacity are the basic pathogenesis of type 2 diabetes mellitus (T2DM). In addition to genetic factors, the...
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Dexamethasone or Dexmedetomidine as Local Anesthetic Adjuvants for Ultrasound-guided Axillary Brachial Plexus Blocks with Nerve Stimulation

Lee MJ, Koo DJ, Choi YS, Lee KC, Kim HY

BACKGROUND: The purpose of this study was to evaluate the effect of dexamethasone or dexmedetomidine added to ropivacaine on the onset and duration of ultrasound-guided axillary brachial plexus blocks (BPB). METHODS:...
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Clinical Analysis of 65 Multiple Primary Cancer Cases

Koo DJ, Yoon DS, Lee JJ, Park CJ

  • KMID: 2095555
  • J Korean Surg Soc.
  • 1999 Jan;56(1):137-142.
BACKGROUND: Multiple primary cancer (MPC), which is defined as the multiple occurrence of malignant neoplasms in the same individual, has been reported as gradually increasing among patients treated for initial...
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Increased Risk of Nonalcoholic Fatty Liver Disease in Individuals with High Weight Variability

Jung I, Koo DJ, Lee MY, Moon SJ, Kwon H, Park SE, Rhee EJ, Lee WY

Background: Weight loss through lifestyle modification is recommended for patients with nonalcoholic fatty liver disease (NAFLD). Recent studies have suggested that repeated loss and gain of weight is associated with...
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Changes in Insulin Resistance Index and the Risk of Liver Fibrosis in Patients with Nonalcoholic Fatty Liver Disease without Diabetes: Kangbuk Samsung Health Study

Koo DJ, Lee MY, Jung I, Moon SJ, Kwon H, Park SE, Rhee EJ, Lee WY

Background: Fibrosis is the most important prognostic factor for nonalcoholic fatty liver disease (NAFLD). Insulin resistance plays a key role of fibrosis progression. We evaluated the association between changes in...
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Coronary Artery Calcium Score as a Sensitive Indicator of Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus: A Long-Term Cohort Study

Koo DJ, Lee MY, Moon SJ, Kwon H, Lee SM, Park SE, Park CY, Lee WY, Oh KW, Cho SR, Jeong YH, Rhee EJ

Background: Coronary artery calcium score (CACS) has become an important tool for evaluating cardiovascular disease (CVD). This study evaluated the significance of CACS for future CVD through more than 10...
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Relationship of Renal Implantation Biopsies and Acute Rejection during Immediate Posttransplantation Period

Lee P, Koo DJ, Lee S, Kim JS, Nam ES, Kim ST, Choi CS

  • KMID: 2144947
  • J Korean Soc Transplant.
  • 1998 Nov;12(2):275-284.
Many factors can be recognized for the acute rejection such as: degree of HLA mismatching, cytokine gene expression, ischemic time, etc. Some authors have suggested the importance of early routine...
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