- Suppressive effect of dehydroepiandrosterone on the development of asthmatic reaction in BALB/c mice
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Cui Y, Choi IS, Koh YI, Koh YA, Lee HC
- KMID: 2285824
- J Asthma Allergy Clin Immunol.
- 2004 Mar;24(1):116-126.
BACKGROUND: Dehydroepiandrosterone (DHEA), an adrenal androgen, may regulate Th1/Th2 cytokines. OBJECTIVE: To determine whether DHEA have a preventive effect against the development of asthma, a Th2-associated disease. MATERIALS AND METHODS: Female BALB/c... -
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- Preventive Effect of Combined Administration of BCG and DHEA against Development of Asthma
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- KMID: 2299653
- Korean J Asthma Allergy Clin Immunol.
- 2005 Dec;25(4):291-298.
BACKGROUND: Both Bacille Calmette-Guerin (BCG) vaccine and dehydroepiandrosterone (DHEA) have a suppressive effect on asthma. OBJECTIVE: To evaluate the effect of BCG and DHEA combination against the development of asthma. METHOD:... -
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- BCG-Induced Dendritic Cell Responses and Suppression of Interleukin-5 Production from T Cells in Atopic Asthmatics
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Choi IS, Lin XH, Koh YA, Cui Y
- KMID: 1785821
- J Korean Med Sci.
- 2008 Aug;23(4):628-634.
- doi: 10.3346/jkms.2008.23.4.628
Bacille Calmette-Guerin (BCG) induces potent Th1 responses with the help of interleukin (IL)-10 and IL-12 released from dendritic cells (DCs), and suppresses Th2- associated allergic reactions. However, there are still... -
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- Inoculation route-dependent effects of BCG on asthmatic airway histology
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Lin XH, Choi IS, Koh YA
- KMID: 1833327
- Korean J Med.
- 2006 Apr;70(4):418-428.
BACKGROUND: Intranasal (i.n.), as compared with subcutaneous (s.c.), BCG vaccination causes a greater suppression of airway eosinophilia. A comprehensive examination is needed to confirm that in various asthma models. METHODS: BALB/c... -
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- Effects of Dehydroepiandrosterone on the Schultz-Dale Reaction and the Th2 Immune Response in Sensitized BALB/c Mice
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- KMID: 2299589
- Korean J Asthma Allergy Clin Immunol.
- 2008 Jun;28(2):121-127.
BACKGROUND: Dehydroepiandrosterone (DHEA) increases the production of interferon (IFN)-gamma, and IFN-gamma suppresses the Th2 response. OBJECTIVE: To investigate whether DHEA suppresses the in vitro allergen-induced response of airway muscles. METHOD: Female BALB/c... -
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- Effects of dehydroepiandrosterone on Th2 cytokine production in peripheral blood mononuclear cells from asthmatics
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Choi IS, Cui Y, Koh YA, Lee HC, Cho YB, Won YH
- KMID: 1100765
- Korean J Intern Med.
- 2008 Dec;23(4):176-181.
- doi: 10.3904/kjim.2008.23.4.176
BACKGROUND/AIMS: The androgen dehydroepiandrosterone (DHEA) attenuates allergic inflammatory airway reactions by down-regulating the Th2 response in mice. The purpose of this study was to investigate whether DHEA suppresses Th2... -
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