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Comparative Statistic Module (CSM) for Significant Gene Selection

Kim YJ, Kim HM, Kim SB, Park C, Kimm K, Koh I

  • KMID: 1515375
  • Genomics Inform.
  • 2004 Dec;2(4):180-183.
Comparative Statistic Module(CSM) provides more reliable list of significant genes to genomics researchers by offering the commonly selected genes and a method of choice by calculating the rank of each...
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The Effect of Increasing Control-to-case Ratio on Statistical Power in a Simulated Case-control SNP Association Study

Kang M, Choi S, Koh I

  • KMID: 1469573
  • Genomics Inform.
  • 2009 Sep;7(3):148-151.
Generally, larger sample size leads to a greater statistical power to detect a significant difference. We may increase the sample size for both case and control in order to obtain...
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MediScore: MEDLINE-based Interactive Scoring of Gene and Disease Associations

Cho HY, Oh B, Lee JK, Kimm K, Koh I

  • KMID: 2053079
  • Genomics Inform.
  • 2004 Sep;2(3):131-133.
MediScore is an information retrieval system, which helps to search for the set of genes associated with a specific disease or the set of diseases associated with a specific gene....
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MEASUREMENT OF ALAR RIM & NOSTRIL SILL LENGTH IN CLEFT LIP AND PROPOSAL OF OPERATIVE METHODS

Koh I, Ahn DK, Kim IG, Uhm KI, Kim DW

  • KMID: 2119311
  • J Korean Soc Plast Reconstr Surg.
  • 1997 Jan;24(1):100-106.
Cleft lip and palate is the most common deformity among the facial congenital anomalies. And although many research and studies of operative methods haute been performed, the actual measurement of...
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Development of Database System for Community Based Home Care in Health Center

Kim J, Kim I, Kim E, Koh I, You H, Chae Y, Jun K, Kim I

  • KMID: 2099642
  • J Korean Soc Med Inform.
  • 2002 Mar;8(1):25-35.
The purpose of this study was to develop a database system for visiting nurses working in a community health center. The final goal of the system is for it to...
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Analysis of unmapped regions associated with long deletions in Korean whole genome sequences based on short read data

Lee Y, Park K, Koh I

While studies aimed at detecting and analyzing indels or single nucleotide polymorphisms within human genomic sequences have been actively conducted, studies on detecting long insertions/deletions are not easy to orchestrate....
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Genetic Variants of IL-13 and IL-4 in the Korean Population: Polymorphisms, Haplotypes and Linkage Disequilibrium

Ryu HJ, Jung HY, Park JS, Kim JW, Kim HT, Park CS, Han BG, Koh I, Park C, Kimm K, Oh B, Lee JK

  • KMID: 2284674
  • Genomics Inform.
  • 2005 Dec;3(4):149-153.
Asthma is an inflammatory airways disease characterized by bronchial hyperresponsiveness and airways obstruction, which results from a complex interaction of genetic and environmental factors. Interleukin (IL)-13 and IL-4 are important...
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Brain Region-Dependent Alternative Splicing of Alzheimer Disease (AD)-Risk Genes Is Associated With Neuropathological Features in AD

Kim S, Han S, Cho Sa, Nho K, Koh I, Lee Y

Purpose: Alzheimer disease (AD) is one of the most complex diseases and is characterized by AD-related neuropathological features, including accumulation of amyloid-β plaques and tau neurofibrillary tangles. Dysregulation of alternative...
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Polymorphisms of ATF6B Are Potentially Associated With FEV1 Decline by Aspirin Provocation in Asthmatics

Park TJ, Kim JH, Pasaje CF, Park BL, Bae JS, Uh ST, Kim YH, Kim MK, Choi IS, Choi BW, Shin HR, Park JS, Koh I, Park CS, Shin HD

PURPOSE: Endoplasmic reticulum (ER) stress has recently been observed to activate NF-kappaB and induce inflammatory responses such as asthma. Activating transcription factor 6beta (ATF6B) is known to regulate ATFalpha-mediated ER...
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Interaction Effects of Lipoprotein Lipase Polymorphisms with Lifestyle on Lipid Levels in a Korean Population: A Cross-sectional Study

Pyun JA, Kim S, Park K, Baik I, Cho NH, Koh I, Lee JY, Cho YS, Kim YJ, Go MJ, Shim E, Kwack K, Shin C

Lipoprotein lipase (LPL) plays an essential role in the regulation of high-density lipoprotein cholesterol (HDLC) and triglyceride levels, which have been closely associated with cardiovascular diseases. Genetic studies in European...
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RNA-Seq for Gene Expression Profiling of Human Necrotizing Enterocolitis: a Pilot Study

Jung K, Koh I, Kim JH, Cheong HS, Park T, Nam SH, Jung SM, Sio CA, Kim SY, Jung E, Lee B, Kim HR, Shin E, Jung SE, Choi CW, Kim BI, Jung E, Shin HD

Necrotizing enterocolitis (NEC) characterized by inflammatory intestinal necrosis is a major cause of mortality and morbidity in newborns. Deep RNA sequencing (RNA-Seq) has recently emerged as a powerful technology enabling...
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