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Natural Killer Cell Activity in Rheumatoid Arthritis Measured by a Single Cell Cytotoxicity Assay

Kim GS, Youn JK, Kim JD, Kim NH

The natural killer(NK) cell activity of mononuclear cells (MNC) from peripheral blood (PB) and synovial fluid (SF) of 40 rheumatoid arthritis(RA) patients was investigated by employing 51-chromium-(51Cr) release microcytotoxicity and...
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Hypersensitivity to Mosquito Bites Associated with Natural Killer Cell-derived Large Granular Lymphocyte Lymphocytosis: A Case Report in Korea

Chung JS, Shin HJ, Lee EY, Cho GJ

  • KMID: 759635
  • Korean J Intern Med.
  • 2003 Mar;18(1):50-52.
Hypersensitivity to mosquito bites (HMB) is characterized by intense skin reactions at bite sites. The pathogenesis of HMB might be related to clonal lymphoproliferation of Epstein-Barr virus DNA-positive natural killer...
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Activated natural killer cell-mediated immunity is required for the inhibition of tumor metastasis by dendritic cell vaccination

Kim A, Noh YW, Kim KD, Jang YS, Choe YK, Lim JS

  • KMID: 1123764
  • Exp Mol Med.
  • 2004 Oct;36(5):428-443.
Immunization with dendritic cells (DCs) pulsed with tumor antigen can activate tumor-specific cytotoxic T lymphocytes (CTL), which is responsible for tumor protection and regression. In this study, we examined whether...
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Natural killer activity and antibody-dependent cellular cytotoxicity in patients with primary lung cancer

Kim SK, Cho CH, Ahn CM, Jang SH, Lee YH, Kim SK, Chang J, Lee BK, Kim SJ, Youn JK

The NK activity and ADCC of peripheral blood mononuclear cell were examined to evaluate the contribution of ADCC and NK activity to host immune response against lung cancer. The NK...
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Increase of NKG2D ligands and sensitivity to NK cell-mediated cytotoxicity of tumor cells by heat shock and ionizing radiation

Kim JY, Son YO, Park SW, Bae JH, Chung JS, Kim HH, Chung BS, Kim SH, Kang CD

  • KMID: 1098081
  • Exp Mol Med.
  • 2006 Oct;38(5):474-484.
In this study, we have investigated if current cancer therapeutic modalities including hyperthermia and ionizing radiation can increase the expression of NKG2D ligands in human cancer cell lines. The expressions...
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Enhancement of antitumor effect using dendritic cells activated with natural killer cells in the presence of Toll-like receptor agonist

Pham TN, Hong CY, Min JJ, Rhee JH, Nguyen TA, Park BC, Yang DH, Park YK, Kim HR, Chung IJ, Kim HJ, Lee JJ

Dendritic cells (DCs) play a role in natural killer (NK) cell activation, while NK cells are also able to activate and mature DCs. Toll-like receptors (TLRs) on the surface of...
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Suppression of Tumor Formation and Induction of Natural Killer Cell Activity in BALB/c Nude Mice by Human B7-1 (CD80) Gene Transfer Subcutaneously Injected with Human Hepatocellular Carcinoma Cells (Huh-7)

Yoon SK, Kim TG, Cho HI, Lee BS, Cho SH, Han NI, Lee YS, Jang JW, Chung KW, Sun HS, Kim BS

  • KMID: 863146
  • Korean J Hepatol.
  • 2003 Jun;9(2):124-134.
BACKGROUND/AIMS: Immunogene therapy is extensively studied for a therapeutic modality of various cancers. This study was conducted to investigate the efficacy of immunogene therapy using the T-cell costimulatory molecule...
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Body Fat Percentage and Natural Killer Cell Activity of Breast and Rectal Cancer Patients after Diagnosis but before Treatment

Kim DS, Jun MH

PURPOSE: To examine the relationship between body fat percentage (BFP) and N-K cell activity (NKCA) in Korean breast and rectal cancer patients just after diagnosis. METHODS: With 35 subjects...
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