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Personalized nutritional management in the transition from non-dialysis dependent chronic kidney disease to dialysis

Narasaki Y, Siu MK, Nguyen M, Kalantar-Zadeh K, Rhee CM

Dialysis has been the dominant treatment regimen in end-stage kidney disease as a means to remove uremic waste products and to maintain electrolyte, acid base, and fluid balance. However, given...
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Cardiac and kidney outcomes after sacubitril-valsartan therapy: recovery of cardiac function relative to kidney function decline

Kim HJ, Yang E, Koh HB, Jhee JH, Park HC, Choi HY

Background: Sacubitril-valsartan reduces the risk of cardiovascular mortality among patients with heart failure with reduced ejection fraction (HFrEF). However, its long-term protective effects on cardiac function with concurrent acute kidney...
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To treat or not to treat: CUBN-associated persistent proteinuria

Choi YY, Ahn YH, Park E, Kim JH, Kang HG, Lee HK

Background: Persistent proteinuria is an important indicator of kidney damage and requires active evaluation and intervention. However, tubular proteinuria of genetic origin typically does not improve with immunosuppression or antiproteinuric...
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Chronic cholesterol crystal embolism: the value of kidney biopsy

Silva ISe, Campos MAG, Santos RF, Silva GEB

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Air pollution can affect kidney disease? Scientific evidence from epidemiology to experimental studies

Park J, Lee W

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Clinical and pathological significance of Orai1 channel expression in human diabetic nephropathy

Kwak Y, Lee JY, Kim JS, Yang JW, Hwang KH, Cha SK, Eom M

Background: Targeted therapies for diabetic nephropathy (DN) are lacking, partly due to their irreversible nature. The role of Orai1, a store-operated Ca2+ channel, in DN remains debated, with conflicting evidence...
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Maternal exposure to airborne particulate matter during pregnancy and lactation induces kidney injury in rat dams and their male offspring: the role of vitamin D in pregnancy and beyond

Son MH, Park E, Yim HE, Nam YJ, Lee YS, Choi EK, Jeong SH, Lee J

Background: Little is known about the transgenerational effects of maternal exposure to fine particulate matter (PM2.5) on offspring kidney health. This study investigated the effect of maternal administration of PM2.5...
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Asymptomatic hematuria in children: Korean Society of Pediatric Nephrology recommendations for diagnosis and management

Park E, Kim SW, Kim SJ, Baek M, Ahn YH, Yang EM, Cho MH, Lee HK, Han KH, Kim YL, Choi M, Kang HG, Suh JS, on behalf of the Hematuria Guideline Development Group

Hematuria is a relatively common condition among school-aged children. Because international guidelines for asymptomatic hematuria in children are unavailable, developing practical guidelines for the diagnosis and management of asymptomatic hematuria...
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Pathogenesis and management of renal fibrosis induced by unilateral ureteral obstruction

Nan QY, Piao SG, Jin JZ, Chung BH, Yang CW, Li C

Regardless of the underlying etiology, renal fibrosis is the final histological outcome of progressive kidney disease. Unilateral ureteral obstruction (UUO) is an ideal and reproducible experimental rodent model of renal...
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Long non-coding RNA MEG3 silencing weakens high glucose-induced mesangial cell injury by decreasing LIN28B expression by sponging and sequestering miR-23c

Rong L, Xue H, Hao J, Liu J, Xu H

Background: Diabetic nephropathy (DN) is a common kidney disease in diabetic patients. Long non-coding RNA maternally expressed gene 3 (MEG3) and microRNA (miR)-23c are reported to be implicated in DN...
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Effect of immunosuppressive agents on clinical outcomes in idiopathic membranous nephropathy

Choi JY, Chin HJ, Lee H, Jeon Y, Lim JH, Jung HY, Cho JH, Kim CD, Kim YL, Park SH

Background: Few comparative studies on the effects of immunosuppressants in patients with idiopathic membranous nephropathy have been conducted. Methods: Data from 489 patients who received conservative treatment or immunosuppressants were...
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Gelsolin amyloidosis associated with the p.D214N gelsolin gene mutation in a Chinese family

Wang S, Li Dy, Xu J, Song Wj, Wang Sx

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The current state of life expectancy of hemodialysis patients in Korea

Ryou S, Yoon HE

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Remaining life expectancy of Korean hemodialysis patients: how much longer can they live?

Park HC, Kim DH, Cho A, Kim BY, Lee M, Kim GO, Kim J, Lee YK

Background: Hemodialysis (HD) patients have a higher mortality rate compared to the general population. However, no study has investigated life expectancy in Korean HD patients so far. Therefore, this study...
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Fasting blood glucose and the risk of all-cause mortality in patients with diabetes mellitus undergoing hemodialysis

Yoon SY, Kim JS, Ko GJ, Choi YJ, Moon JY, Jeong K, Hwang HS

Background: Glycemic control is particularly important in hemodialysis (HD) patients with diabetes mellitus (DM). Although fasting blood glucose (FBG) level is an important indicator of glycemic control, a clear target...
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