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The 5th Asia Pacific AKI CRRT 2023: Best Movement to Critical Care, Save Lives

Kang KP

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Artificial intelligence and machine learning’s role in sepsis-associated acute kidney injury

Cheungpasitporn W, Thongprayoon C, Kashani KB

Sepsis-associated acute kidney injury (SA-AKI) is a serious complication in critically ill patients, resulting in higher mortality, morbidity, and cost. The intricate pathophysiology of SA-AKI requires vigilant clinical monitoring and...
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Biomarkers in pursuit of precision medicine for acute kidney injury: hard to get rid of customs

Lin KM, Su CC, Chen JY, Pan SY, Chuang MH, Lin CJ, Wu CJ, Pan HC, Wu VC

Traditional acute kidney injury (AKI) classifications, which are centered around semi-anatomical lines, can no longer capture the complexity of AKI. By employing strategies to identify predictive and prognostic enrichment targets,...
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Differences in the incidence, characteristics, and outcomes of patients with acute kidney injury in the medical and surgical intensive care units

Lee Y, Kim T, Kim DE, Jo EM, Kim DW, Kim HJ, Seong EY, Song SH, Rhee H

Background: Though acute kidney injury (AKI) is a prevalent complication in critically ill patients, knowledge on the epidemiological differences and clinical characteristics of patients with AKI admitted to medical and...
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Unveiling the enigma of acute kidney disease: predicting prognosis, exploring interventions, and embracing a multidisciplinary approach

Pan SY, Huang TTM, Jiang ZH, Lin LC, Tsai IJ, Wu TL, Hsu CY, Wang T, Chen HC, Lin YF, Wu VC

Acute kidney disease (AKD) is a critical transitional period between acute kidney injury and chronic kidney disease. The incidence of AKD following acute kidney injury is approximately 33.6%, and it...
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Time-restricted feeding protects against cisplatin-induced acute kidney injury in mice

Jang KW, Kim YS, Kim MJ, Kim SR, Lee DW, Lee SB, Kim IY

Background: Time-restricted feeding (TRF), devoid of calorie restriction, is acknowledged for promoting metabolic health and mitigating various chronic metabolic diseases. While TRF exhibits widespread benefits across multiple tissues, there is...
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Long-term outcomes of acute kidney injury in acute decompensated heart failure: identifying true cardiorenal syndrome and unveiling prognostic significance

Thanapongsatorn P, Tanomchartchai A, Assavahanrit J

Background: Cardiorenal syndrome (CRS) type 1 defined as acute kidney injury (AKI) in acute decompensated heart failure (ADHF), is complicated due to diverse definitions. Recently, a more precise CRS type...
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The role of nafamostat mesylate anticoagulation in continuous kidney replacement therapy for critically ill patients with bleeding tendencies: a retrospective study on patient outcomes and safety

Kim T, Kim DE, Jo EM, Lee Y, Kim DW, Kim HJ, Seong EY, Song SH, Rhee H

Background: Continuous kidney replacement therapy (CKRT) is crucial in the management of acute kidney injury in intensive care units (ICUs). Nonetheless, the optimal anticoagulation strategy for patients with bleeding tendencies...
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A machine learning-based approach for predicting renal function recovery in general ward patients with acute kidney injury

Cho NJ, Jeong I, Kim Y, Kim DO, Ahn SJ, Kang SH, Gil HW, Lee H

Background: Acute kidney injury (AKI) is a significant challenge in healthcare. While there are considerable researches dedicated to AKI patients, a crucial factor in their renal function recovery, is often...
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Plasma presepsin for mortality prediction in patients with sepsis-associated acute kidney injury requiring continuous kidney replacement therapy

Lee GB, Lee JW, Yoon SH, Hwang WM, Yun SR, Koh DH, Park Y

Background: The reliability of presepsin as a biomarker of sepsis may be reduced in patients with acute kidney injury (AKI) requiring continuous kidney replacement therapy (CKRT). This study analyzed the...
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The effect of pharmacist-led medication therapy management in the multidisciplinary care of acute kidney injury survivors

Wang T, Kang HC, Wu CC, Wu TL, Huang CF, Wu VC

Background: The Acute Disease Quality Initiative advocates multidisciplinary care for the survivors of acute kidney injury (AKI). The bundled care strategy recognizes the role of pharmacists. However, their specific contributions...
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Association between systemic inflammation biomarkers and mortality in patients with sepsis-associated acute kidney injury receiving intensive care and continuous kidney replacement therapy: results from the RENERGY (REsearches for NEphRology and epidemioloGY) study

Jung CY, Jung J, Lim JH, Paek JH, Kim K, Ban TH, Park JY, Kim H, Kim YC, Baek CH

Background: Identifying risk factors and improving prognostication for mortality among patients with sepsis-associated acute kidney injury (AKI) undergoing continuous kidney replacement therapy (CKRT) is important in improving the adverse prognosis...
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Phosphate level predicts mortality in acute kidney injury patients undergoing continuous kidney replacement therapy and has a U-shaped association with mortality in patients with high disease severity: a multicenter retrospective study

Lee YH, Lee S, Seo YJ, Jung J, Lee J, Park JY, Ban TH, Park WY, Lee SW, Kim K, Kim KM, Kim H, Choi JY, Cho JH, Kim YC, Lim JH

Background: This study investigated the association between serum phosphate level and mortality in acute kidney injury (AKI) patients undergoing continuous kidney replacement therapy (CKRT) and evaluated whether this association differed...
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Validation of prediction model for successful discontinuation of continuous renal replacement therapy: a multicenter cohort study

Jeon J, Ko EJ, Park H, Baeg SI, Kim HD, Min JW, Koh ES, Lee K, Kang D, Cho J, Lee JE, Huh W, Chung BH, Jang HR

Background: Continuous renal replacement therapy (CRRT) has become the standard modality of renal replacement therapy (RRT) in critically ill patients. However, consensus is lacking regarding the criteria for discontinuing CRRT....
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Mortality of elderly patients with acute kidney injury undergoing continuous renal replacement therapy: is age a risk factor?

Kim JH, Eum SH, Kim HW, Min JW, Koh ES, Ko EJ, Kim HD, Chung BH, Shin SJ, Yang CW, Yoon HE

Background: Whether advanced age is associated with poor outcomes of elderly patients with acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) is controversial. This study aimed to evaluate...
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