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Hypermethylation of Tumor-related Genes in Genitourinary Cancer Cell Lines

Chung WB, Hong SH, Kim JA, Sohn YK, Kim BW, Kim JW

Hypermethylation of CpG island is a common mechanism for the inactivation of tumor-related genes. In the present study, we analyzed 13 genitourinary cancer cell lines for aberrant DNA methylation of...
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IL-4 inhibits proliferation of renal carcinoma cells by increasing the expression of p21WAF1 and IRF-1

Yu SJ, Kim HS, Cho SW, Sohn J

  • KMID: 1094082
  • Exp Mol Med.
  • 2004 Aug;36(4):372-379.
Interleukin (IL)-4 inhibits proliferation of several human cancer cell lines in vitro. Although IL-4 is known to regulate proliferation of lymphocytes by modulating p27KIP1 expression, the mechanism involved in the...
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A Case of Birt-Hogg-Dube Syndrome

Kim EH, Jeong SY, Kim HJ, Kim YC

Birt-Hogg-Dube syndrome (BHDS) is an autosomal dominant genodermatosis characterized by cutaneous hair follicle tumors (fibrofolliculoma or trichodiscoma), pulmonary cysts, and increased risk of renal neoplasia. The genetic alteration for BHDS...
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