- IL-10 Mediates Rosiglitazone-Induced Kidney Protection in Cisplatin Nephrotoxicity
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Kim MG, Yang HN, Kim HW, Jo SK, Cho WY, Kim HK
- KMID: 1792925
- J Korean Med Sci.
- 2010 Apr;25(4):557-563.
- doi: 10.3346/jkms.2010.25.4.557
Cisplatin, a major anti-neoplastic drug, is known to be nephrotoxic and inflammation-inducing. A peroxisome proliferator-activated receptor gamma agonist, regulating lipid metabolism, has known to have anti-inflammatory effect, but the protection... -
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- Concomitant inhibition of renin angiotensin system and Toll-like receptor 2 attenuates renal injury in unilateral ureteral obstructed mice
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Chung S, Jeong JY, Chang YK, Choi DE, Na KR, Lim BJ, Lee KW
- KMID: 2373808
- Korean J Intern Med.
- 2016 Mar;31(2):323-334.
- doi: 10.3904/kjim.2015.004
BACKGROUND/AIMS: There has been controversy about the role of Toll-like receptor 2 (TLR2) in renal injury following ureteric obstruction. Although inhibition of the renin angiotensin system (RAS) reduces TLR2 expression... -
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- B6C3F1 mice exposed to ozone with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate showed toxicities through alterations of NF-kappaB, AP-1, Nrf2, and osteopontin
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Kim MY, Song KS, Park GH, Chang SH, Kim HW, Park JH, Jin H, Eu KJ, Cho HS, Kang G, Kim YC, Cho MH
- KMID: 1120069
- J Vet Sci.
- 2004 Jun;5(2):131-137.
Toxic effects of ozone, 4-(N-methyl-N-nitrosamino)-1-(3- pyridyl)-1-butanone (NNK), and/or dibutyl phthalate (DBP) were examined through NF-kappaB, AP-1, Nrf2, and osteopontin (OPN) in lungs and livers of B6C3F1 mice. Electrophoretic mobility shift... -
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