- Inhibition of Nicotinamide Phosphoribosyltransferase Induces Apoptosis in Estrogen Receptor-Positive MCF-7 Breast Cancer Cells
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Alaee M, Khaghani S, Behroozfar K, Hesari Z, Ghorbanhosseini SS, Nourbakhsh M
- KMID: 2379395
- J Breast Cancer.
- 2017 Mar;20(1):20-26.
- doi: 10.4048/jbc.2017.20.1.20
PURPOSE: Tumor cells have increased turnover of nicotinamide adenine dinucleotide (NADâº), the main coenzyme in processes including adenosine diphosphate-ribosylation, deacetylation, and calcium mobilization. NAD⺠is predominantly synthesized in human cells... -
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