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Differentiation characteristics of cholesteatoma epithelium determined by expression of transglutaminase isoenzymes

Chang CS, Jun BH, Song KY, Kim IG

Transglutaminase (TGase) isoenzymes are involved in the process of the differentiation and cornification of keratinocytes in the epidermis. This study investigates the presence and localization of three TGase isoenzymes to...
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Expression of Neutrophil Gelatinase-Associated Lipocalin in Calcium-Induced Keratinocyte Differentiation

Lee JH, Kye KC, Seo EY, Lee K, Lee SK, Lim JS, Seo YJ, Kim CD, Park JK

In a previous search for the differentially expressed genes in keratinocyte differentiation, we identified neutrophil gelatinase-associated lipocalin (NGAL) as a calcium- induced gene. In this study, we further verified the...
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Calpain inhibitors reduce the cornified cell envelope formation by inhibiting proteolytic processing of transglutaminase 1

Kim SY, Bae CD

  • KMID: 755018
  • Exp Mol Med.
  • 1998 Dec;30(4):257-262.
Calpain I (mu-calpain) and II (m-calpain) are well known calcium-activated neutral cysteine proteases. Many reports have shown that activation of calpain is related to cataract formation, neuronal degeneration, blood clotting, ...
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