- Autocrine Extracellular Signal-regulated Kinase Activation in Normal Human Keratinocytes is not Interrupted by Calcium Triggering and is Involved in the Control of Cell Cycle at the Early Stage of Calciuminduced Differentiation
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Park GT, Kim HY, Kim EK, Yang JM
- KMID: 1713190
- J Korean Med Sci.
- 2007 Apr;22(2):290-297.
- doi: 10.3346/jkms.2007.22.2.290
Normal human epidermal keratinocytes (NHEK) respond to the autocrine activated extracellular signal-regulated kinase (ERK) signaling pathway, which contributes to the survival of keratinocytes. However, during the condition of calcium-induced differentiation,... -
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- The effects of wild type p53 tumor suppressor gene expression on the normal human cervical epithelial cells or human epidermal keratinocytes transformed with human papillomavirus type 16 DNA
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Kim KH, Park TK, Yoon DJ, Kim YS
- KMID: 1123184
- Yonsei Med J.
- 1995 Jun;36(3):287-298.
- doi: 10.3349/ymj.1995.36.3.287
The inactivation of p53 and p105RB by viral proteins or by mutations plays a key role in the oncogenesis of cervical carcinoma. The E6 and E7 proteins of HPV type... -
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- Expression of N-terminal truncated desmoglein 3 (Delta NDg3) in epidermis and its role in keratinocyte differentiation
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Lee JS, Yoon HK, Sohn KC, Back SJ, Kee SH, Seo YJ, Park JK, Kim CD, Lee JH
- KMID: 756285
- Exp Mol Med.
- 2009 Jan;41(1):42-50.
- doi: 10.3858/emm.2009.41.1.006
During a search for keratinocyte differentiation-related genes, we obtained a cDNA fragment from the 5'-untranslated region of a previously identified splicing variant of desmoglein 3 (Dg3). This transcript encodes a... -
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- Differential Expression of TGF-beta Isoforms During Differentiation of HaCaT Human Keratinocyte Cells: Implication for the Separate Role in Epidermal Differentiation
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Cho HR, Hong SB, Kim YI, Lee JW, Kim NI
- KMID: 1778568
- J Korean Med Sci.
- 2004 Dec;19(6):853-858.
- doi: 10.3346/jkms.2004.19.6.853
The three mammalian isoforms of transforming growth factor-beta (TGF-beta1, beta2, beta3) are potent regulators of cell growth, differentiation, and extracellular matrix deposition. To study their role in skin differentiation, we... -
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