- Effect of 12-O-tetradecanoylphorbol 13-acetate (TPA) on the Expression of Keratin in HaCaT Cells
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Ahn SH, Lee SH, Kim DK, Kim JY
- KMID: 1610762
- Korean J Anat.
- 2003 Aug;36(4):271-282.
In human skin, specific keratin markers reflect on normal differentiation and pathologic conditions. This experiment focused on the expressional pattern of keratin 10 (K10: normal differentiation marker), and keratin 8... -
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- 12-O-Tetradecanoylphorbol-13-Acetate Induces Keratin 8 Phosphorylation and Reorganization via Expression of Transglutaminase-2
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Lee EJ, Park MK, Kim HJ, Kang JH, Kim YR, Kang GJ, Byun HJ, Lee CH
- KMID: 2170651
- Biomol Ther.
- 2014 Mar;22(2):122-128.
The stiffness of cancer cells is attributable to intermediate filaments such as keratin. Perinuclear reorganization via phosphorylation of specific serine residue in keratin is implicated in the deformability of metastatic... -
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- Ethacrynic Acid Inhibits Sphingosylphosphorylcholine-Induced Keratin 8 Phosphorylation and Reorganization via Transglutaminase-2 Inhibition
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Byun HJ, Kang KJ, Park MK, Lee HJ, Kang JH, Lee EJ, Kim YR, Kim HJ, Kim YW, Jung KC, Kim SY, Lee CH
- KMID: 2048303
- Biomol Ther.
- 2013 Sep;21(5):338-342.
Sphingosylphosphorylcholine (SPC) is significantly increased in the malicious ascites of tumor patients and induces perinuclear reorganization of keratin 8 (K8) filaments in PANC-1 cells. The reorganization contributes to the viscoelasticity... -
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- Co-relationship between Expression of Keratins and Vimentin in Breast Cancer Tissures and Metastases of Breast Cancer
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Jegal YJ, Yoon JH, Park CS
- KMID: 2006621
- J Korean Breast Cancer Soc.
- 2003 Sep;6(3):148-154.
- doi: 10.4048/jkbcs.2003.6.3.148
PURPOSE: the most important biological behavior of breast cancer is its invasive potential and many efforts was made to reveal the factors related with the invasiveness of breast cancer cells.... -
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- Clinical Significance of the Urinary Bladder Cancer Antigen (UBCTM) Test in the Diagnosis of Bladder Cancer
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Moon YC, Ryu DS, Oh TH
- KMID: 2292518
- Korean J Urol.
- 2002 Dec;43(12):1024-1028.
PURPOSE: A new quantitative tumor marker, based on the combined measurement of urinary fragments of cytokeratin 8 and 18, namely the urinary bladder cancer antigen (UBCTM) test, has been proposed... -
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- Cytokeratin Autoantibodies: Useful Serologic Markers for Toluene Diisocyanate-Induced Asthma
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Ye YM, Nahm DH, Kim CW, Kim HR, Hong CS, Park CS, Suh CH, Park HS
- KMID: 1777164
- Yonsei Med J.
- 2006 Dec;47(6):773-781.
- doi: 10.3349/ymj.2006.47.6.773
To evaluate the clinical significance of autoantibodies to three major epithelial cytokeratins (CK) -- CK8, CK18, and CK19 -- we compared 66 patients with toluene diisocyanate (TDI)-induced asthma (group I)... -
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- Expression of Cytokeratin Subtypes in Advanced Laryngeal Carcinoma and Its Relationship to p53 and Human Papilloma Virus
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Jang HS, Kim MS, Sun DI, Song SH, Lee JH, Cho SH
- KMID: 1977699
- Korean J Otolaryngol-Head Neck Surg.
- 1999 Dec;42(12):1533-1540.
BACKGROUND AND OBJECTIVES: This study investigated the expression of cytokeratin 8, 18, 19 with low molecular weight, which have been classified as a group of simple epithelium-related marker for advanced... -
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- Analysis of Airway Epithelial Cell Autoantigens Recognized by IgG Autoantibodies from Patients with Severe Asthma and Chronic Obstructive Pulmonary Disease
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- KMID: 2346806
- Korean J Asthma Allergy Clin Immunol.
- 2009 Dec;29(4):249-255.
BACKGROUND: The presence of circulating autoantibodies to airway epithelial cells has been reported in patients with asthma and chronic obstructive pulmonary disease (COPD). OBJECTIVE: To evaluate the possibility of a common... -
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- Incidence and Prognostic Implications of Lymph Node Micrometastases in Patients with Submucosal Gastric Cancer
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Kim YK, Choi HJ, Kim YH, Jung GJ, Kim SS, Hong SH
- KMID: 1895842
- J Korean Surg Soc.
- 2001 Aug;61(2):158-163.
PURPOSE: Whereas lymph node metastasis in gastric cancer is an important prognostic factor, the prognostic relevance of occult tumor cells in lymph nodes has not yet been elucidated. The aims... -
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- Time-course Transcriptional Profiling of Human Amniotic Fluid-derived Stem Cells Using Microarray
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Kim YW, Kim HJ, Bae SM, Kim YJ, Shin JC, Chun HJ, Rhie JW, Kim J, Kim H, Ahn WS
- KMID: 2165963
- Cancer Res Treat.
- 2010 Jun;42(2):82-94.
PURPOSE: To maintain the homeostasis of stem cells and prevent their ability to initiate tumorigenesis, it is important to identify and modify factors that prevent or accelerate stem cell senescence.... -
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- Diagnostic Value of Serum Cytokeratin 8, 18 and 19 in Lung Cancer
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Choi CM, Kim WJ, Oh JY, Kang YA, Yoo CG, Lee CT, Kim YW, Han SK, Shim YS
- KMID: 2318434
- Tuberc Respir Dis.
- 2003 Oct;55(4):388-394.
BACKGROUND: Monoclonal antibodies directed against well-known epitopes on cytokeratin (CK) 8, 18 and 19 (Monototal) have been used in the development of a new diagnostic tool for lung cancer. In... -
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- Clinical Application of Serum CEA, SCC, Cyfra2l-1, and TPA in Lung Cancer
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Lee JH, Kim KC, Lee SJ, Lee JK, Jo SJ, Kwon KY, Han SB, Jeon YJ
- KMID: 2318058
- Tuberc Respir Dis.
- 1997 Aug;44(4):785-795.
BACKGROUND: Tumor markers have been used in diagnosis, predicting the extent of disease, monitering recurrence after therapy and prediction of prognosis. But the utility of markers in lung cancer has... -
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