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Organotypic Culture of HaCaT cells: Use of Dermal Substrate that Combines de-epidermized Dermis with Fibroblast-populated Collagen Matrix

Cho KH, Lee DY, Park KC, Cho KH

BACKGROUND: The immortalized human keratinocyte line, HaCaT cells have been widely used as substitutes for normal epidermal keratinocytes. Recently, reconstruction of a skin equivalent using HaCaT cells showed a multilayered...
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A Case of Pachyonychia Congenita

Park HS, Youn SJ, Yang JM, Lee ES

  • KMID: 2302813
  • Korean J Dermatol.
  • 2004 Oct;42(10):1372-1374.
Pachyonychia congenita is an uncommon genodermatosis of abnormal keratinization characterized by dystrophic nails and hyperkeratosis of the palms, soles, oral mucosa, and hair follicles. Mutations in keratin 6, 16, and...
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Meibography and Immunohistochemistric Structures in Animal Models

Lee HK, Woo IH, Kang B, Eom YS, Kang SY, Hwang HS, Kim HM, Song JS

PURPOSE: We evaluated differences in the meibographic findings and immunohistochemical structures of mice, rats, and rabbits (commonly used in animal experiments). METHODS: Meibomian gland images were taken using an animal meibograph...
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The Amelioration Effect of the Ethanolic Extract of Cnidium officinale in Mice with Imiquimod-induced Psoriasis-like Skin Lesion

Lee YJ, Hong IK, Kim H, Heo SI, Kwon DJ, Ahn WG, Kim YH, Seo EJ, Han SI, Cho HJ, Kim SY, Yang H

Psoriasis is an auto-immune skin disease, which is characterized by the excessive generation of plaques on the skin with typically a long-lasting red, itchy and scaly symptoms. Imiquimod, which has...
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Clinicopathlogic and Immunohistochemical Characteristics of Triple Negative Invasive Lobular Carcinoma

Koo JS, Jung W

PURPOSE: Our study is performed to find out clinicopathlogic and immunohistochemical (IHC) characteristics of triple negative invasive lobular carcinoma (ILC), as has been demonstrated in their invasive ductal counterparts. MATERIALS...
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Expression of the Markers for the Mammary Stem Cells and the Cellular Lineages of the Mammary Gland on Ductal Carcinoma In Situ

Jo BH, Kim HJ, Kim YJ, Park Y, Lee IK, Kim DI, Lee WH, Yoon SO

PURPOSE: Breast Cancer is an inter-tumoral and intra-tumoral heterogeneous disease. It remains unclear whether this heterogeneity results from different target cells or from different subsets of genetic abnormalities, otherwise from...
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