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Organotypic Culture of HaCaT cells: Use of Dermal Substrate that Combines de-epidermized Dermis with Fibroblast-populated Collagen Matrix

Cho KH, Lee DY, Park KC, Cho KH

BACKGROUND: The immortalized human keratinocyte line, HaCaT cells have been widely used as substitutes for normal epidermal keratinocytes. Recently, reconstruction of a skin equivalent using HaCaT cells showed a multilayered...
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Expression of Epidermal Protein Antigens and Basement Membrane Components in Human Epidermis Reconstructed by Culture

Cho KH, Lee DY, Eun HC, Park KC, Youn JI

  • KMID: 1891567
  • Korean J Dermatol.
  • 1996 Apr;34(2):264-272.
BACKGROUND: A number of in vitro skin models have been developed for the purpose of the screening of cosmetics, pharmaceuticals, and environmental chemicals. To mimic the skin in vivo, a...
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The Effects of Adipose Tissue-Derived Mesenchymal Stem Cells on the Formation ofEpidermis and Basement Membrane in Artificial Skin Models

Byun HJ, Lee SH, Kim JE, Kim YK, Cho KH

  • KMID: 1484221
  • Korean J Dermatol.
  • 2008 Sep;46(9):1186-1193.
BACKGROUND: There is an increasing need for making a more ideal artificial skin model. OBJECTIVE: To evaluate the effects of adipose tissue-derived mesenchymal stem cells (ATMSC) on the formation of epidermis...
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Effects of Calcipotriol ( MC 903 ) on Proliferation and Differentiation of Cultured Human Epidermal Keratinocytes

Lee DY, Cho KH, Minn KW, Son YS

  • KMID: 2303526
  • Korean J Dermatol.
  • 1996 Dec;34(6):942-952.
BACKGROUND: Calcipotriol(MC903), a new vitamin D(3) analogue, has been reported to be effective in the treatment of patients with psoriasis. OBJECTIVE: The purpose of this study is to examine the effects...
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Kinetin Improves Barrier Function of the Skin by Modulating Keratinocyte Differentiation Markers

An S, Cha HJ, Ko JM, Han H, Kim SY, Kim KS, Lee SJ, An IS, Kim S, Youn HJ, Ahn KJ, Kim SY

BACKGROUND: Kinetin is a plant hormone that regulates growth and differentiation. Keratinocytes, the basic building blocks of the epidermis, function in maintaining the skin barrier. OBJECTIVE: We examined whether kinetin induces...
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A case of isolated metastatic hepatocellular carcinoma arising from the pelvic bone

Jung KS, Park KH, Chon YE, Lee SR, Park YN, Lee DY, Seong JS, Park JY

Reports of metastatic hepatocellular carcinoma (HCC) without a primary liver tumor are rare. Here we present a case of isolated HCC that had metastasized to the pelvic bone without a...
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