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Correlation of Early Outcomes and Intradiscal Interleukin-6 Expression in Lumbar Fusion Patients

Koerner JD, Markova DZ, Schroeder , Antonacci , Mendelis J, Vaccaro AR, Anderson D, Kepler CK

Objective: To determine if there is correlation between intradiscal levels of interleukin-6 (IL-6) and early outcome measures in patients undergoing lumbar fusion for painful disc degeneration. Methods: Intervertebral disc tissue was...
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Significance of Facet Fluid Index in Anterior Cervical Degenerative Spondylolisthesis

Lee Y, Heard JC, Lambrechts MJ, Kern N, Wiafe B, Goodman P, Mangan JJ, Canseco JA, Kurd MF, Kaye ID, Hilibrand AS, Vaccaro AR, Kepler CK, Schroeder GD, Rihn JA

Study Design: Retrospective cohort study. Purpose: To correlate cervical facet fluid characteristics to radiographic spondylolisthesis, determine if facet fluid is associated with instability in cervical degenerative spondylolisthesis, and examine whether vertebral...
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Utility of Seated Lateral Radiographs in the Diagnosis and Classification of Lumbar Degenerative Spondylolisthesis

Issa TZ, Lee Y, Berthiaume E, Lambrechts MJ, Zaworski C, Qadiri QS, Spracklen H, Padovano R, Weber J, Mangan JJ, Canseco JA, Woods BI, Kaye ID, Hilibrand AS, Kepler CK, Vaccaro AR, Schroeder GD, Lee JK

Study Design: Retrospective cohort study. Purpose: Our goal was to determine which radiographic images are most essential for degenerative spondylolisthesis (DS) classification and instability detection. Overview of Literature: The heterogeneity in DS...
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Comparison of Surgical Outcomes of the Posterior and Combined Approaches for Repair of Cervical Fractures in Ankylosing Spondylitis

Luksanapruksa P, Millhouse , Carlson V, Ariyawatkul T, Heller J, Kepler CK

STUDY DESIGN: Retrospective cohort study. PURPOSE: To evaluate surgical outcomes and complications of cervical spine fractures in ankylosing spondylitis (CAS) patients who were treated using either the posterior (P) or combined...
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How Does the Severity of Neuroforaminal Compression in Cervical Radiculopathy Affect Outcomes of Anterior Cervical Discectomy and Fusion

Lambrechts MJ, Issa TZ, Lee Y, Tran KS, Heard J, Purtill C, Fried TB, Oh S, Kim E, Mangan JJ, Canseco JA, Kaye ID, Rihn JA, Hilibrand AS, Vaccaro AR, Kepler CK, Schroeder GD

Study Design: This study is a retrospective cohort study. Purpose: This study aims to determine whether preoperative neuroforaminal stenosis (FS) severity is associated with motor function patient-reported outcome measures (PROMs) following...
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Inhibition of Neurogenic Inflammatory Pathways Associated with the Reduction in Discogenic Back Pain

Canseco JA, Levy HA, Karamian BA, Blaber O, Chang M, Patel N, Curran J, Hilibrand AS, Schroeder GD, Vaccaro AR, Markova DZ, Surrey DE, Kepler CK

Study Design: Retrospective cohort study. Purpose: This study aimed to determine whether the initiation of anti-calcitonin gene-related peptide (CGRP inhibitor) medication therapy for migraines was also associated with improvements in back/neck...
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