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A feasibility study on maintenance of docetaxel after paclitaxel-carboplatin chemotherapy in patients with advanced ovarian cancer

Isonishi S, Suzuki M, Nagano H, Takagi K, Shimauchi , Kawabata M, Ochiai K

OBJECTIVE: To test the concept of taxane sequencing, this feasibility trial evaluated maintenance of docetaxel after paclitaxel and carboplatin combination chemotherapy in patients with stage IC-IV ovarian cancer. METHODS: All patients...
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Possible Role of Sonic Hedgehog and Epithelial-Mesenchymal Transition in Renal Cell Cancer Progression

Behnsawy H, Shigemura , Meligy FY, Yamamichi , Yamashita , Haung WC, Li X, Miyake H, Tanaka K, Kawabata M, Shirakawa , Fujisawa M

PURPOSE: Sonic hedgehog (Shh) signaling and epithelial-mesenchymal transition (EMT) are both known to relate to cancer progression. The purpose of this study was to investigate the role of Shh signaling...
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