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Cysteinyl Leukotrienes and Their Receptors; Emerging Concepts

Kanaoka Y, Boyce JA

Cysteinyl leukotrienes (cys-LTs) are potent mediators of inflammation derived from arachidonic acid through the 5-lipoxygenase/leukotriene C4 synthase pathway. The derivation of their chemical structures and identification of their pharmacologic properties...
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