- Physiological, Pharmacological and Toxicological Implications of Heterodimeric Amino Acid Transporters
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Kanai Y, Endou H
- KMID: 2285295
- Korean J Physiol Pharmacol.
- 2004 Jun;8(3):117-128.
The heterodimeric amino acid transporter family is a subfamily of SLC7 solute transporter family which includes 14-transmembrane cationic amino acid transporters and 12-transmembrane heterodimeric amino acid transporters. The members of... -
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- Prognostication of early-onset endometrioid endometrial cancer based on genome-wide DNA methylation profiles
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Hirano T, Arai E, Fujimoto M, Nakayama Y, Tian Y, Ito N, Makabe T, Yamagami W, Susumu N, Aoki D, Kanai Y
- KMID: 2537965
- J Gynecol Oncol.
- 2022 Nov;33(6):e74.
- doi: 10.3802/jgo.2022.33.e74
Objective The aim of this study was to establish criteria that would indicate whether fertility preservation therapy would likely be safe for patients aged 40 years or less with endometrioid endometrial... -
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- Improved Stability and Practicality for Synthesis of 4-Borono-2-[ 18F] fluoro-L-phenylalanine by Combination of [ 18 O]O 2 Single-Use and [ 18 F]CH 3 COOF Labeling Agents
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Naka S, Watanabe T, Kanai Y, Watabe T, Tatsumi M, Kato H, Shimosegawa E, Hatazawa J
- KMID: 2528459
- Nucl Med Mol Imaging.
- 2022 Apr;56(2):86-95.
- doi: 10.1007/s13139-021-00719-1
Purpose 4-Borono-2-[ 18 F]fluoro-L-phenylalanine ([ 18 F]FBPA) synthesized with [ 18 F]F2 , produced using the 18 O(p, n) 18 F reaction, has been reported for increasing radioactivity. However, a... -
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- An ultrastructural study on cytotoxic effects of mono(2-ethylhexyl) phthalate (MEHP) on testes in Shiba goat in vitro
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Andriana B, Tay TW, Maki I, Awal MA, Kanai Y, Kurohmaru , Hayashi Y
- KMID: 1099837
- J Vet Sci.
- 2004 Sep;5(3):235-240.
In this study, the effects of mono(2-ethylhexyl) phthalate (MEHP), one of metabolites of di(2-ethylhexyl) phthalate, on immature Shiba goat testes in vitro were examined. The testes of 2-month-old Shiba goats... -
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- JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells
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Choi DW, Kim DK, Kanai Y, Wempe MF, Endou H, Kim JK
- KMID: 2395254
- Korean J Physiol Pharmacol.
- 2017 Nov;21(6):599-607.
- doi: 10.4196/kjpp.2017.21.6.599
Most normal cells express L-type amino acid transporter 2 (LAT2). However, L-type amino acid transporter 1 (LAT1) is highly expressed in many tumor cells and presumed to support their increased... -
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