- Effectiveness in Switching from Antipsychotic Polypharmacy to Monotherapy in Patients with Schizophrenia: A Case Series
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Kamei H, Yamada H, Hatano M, Hanya M, Yamada S, Iwata N
- KMID: 2502138
- Clin Psychopharmacol Neurosci.
- 2020 Feb;18(1):159-163.
- doi: 10.9758/cpn.2020.18.1.159
In Japan, drug therapy for schizophrenia is characterized by high-dose antipsychotic polypharmacy, which is an uncommon approach internationally. In this study, we reduced the number of antipsychotic agents in 5... -
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- Effect of Scopolamine Butylbromide on Clozapine-induced Hypersalivation in Schizophrenic Patients: A Case Series
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Takeuchi I, Suzuki T, Kishi T, Kanamori D, Hanya M, Uno J, Fujita K, Kamei H
- KMID: 2171071
- Clin Psychopharmacol Neurosci.
- 2015 Apr;13(1):109-112.
- doi: 10.9758/cpn.2015.13.1.109
Clozapine has been demonstrated to be useful for treating refractory schizophrenia. However, hypersalivation occurs in 31.0-97.4% of the patients treated with clozapine. Accordingly, some patients who are disturbed by their... -
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- Effect of Adenine on Clozapine-induced Neutropenia in Patients with Schizophrenia: A Preliminary Study
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Takeuchi I, Kishi T, Hanya M, Uno J, Fujita K, Kamei H
- KMID: 2171046
- Clin Psychopharmacol Neurosci.
- 2015 Aug;13(2):157-162.
- doi: 10.9758/cpn.2015.13.2.157
OBJECTIVE: This study examined the utility of adenine for preventing clozapine-induced neutropenia. METHODS: This retrospective study examined the effect of adenine on clozapine-induced neutropenia in patients with treatment-resistant schizophrenia and was... -
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- Acceptance of the Deltoid Muscle Injection of Aripiprazole Long-acting Injectable in the Patients with Schizophrenia
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Kamei H, Homma Y, Takeuchi I, Hajitsu G, Tozawa K, Hatano M, Fukui A, Hanya M, Yamada S, Iwata N
- KMID: 2502126
- Clin Psychopharmacol Neurosci.
- 2020 Feb;18(1):49-57.
- doi: 10.9758/cpn.2020.18.1.49
Objective: To improve poor medication adherence in schizophrenic patients, long-acting injectable (LAI) antipsychotics are used. However, it has not yet become common in Japan. Recently, aripiprazole LAI was approved for... -
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- Comparison of the Effects of a Brand-name Drug and Its Generic Drug on the Quality of Life of Alzheimer's Disease Patients
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Sakakibara M, Kido M, Kuribayashi J, Okada H, Igarashi A, Kamei H, Nabeshima
- KMID: 2171049
- Clin Psychopharmacol Neurosci.
- 2015 Aug;13(2):174-179.
- doi: 10.9758/cpn.2015.13.2.174
OBJECTIVE: The pharmacological effects of generic (GE) donepezil are the same as Aricept, its brand-name counterpart. However, little is known as to whether these two drugs provide the same quality... -
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- Assessment of Switching to Suvorexant versus the Use of Add-on Suvorexant in Combination with Benzodiazepine Receptor Agonists in Insomnia Patients: A Retrospective Study
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Hatano M, Kamei H, Inagaki R, Matsuzaki , Hanya M, Yamada S, Iwata N
- KMID: 2412387
- Clin Psychopharmacol Neurosci.
- 2018 May;16(2):184-189.
- doi: 10.9758/cpn.2018.16.2.184
OBJECTIVE: Suvorexant is a novel hypnotic drug that does not interact with the conventional γ-aminobutyric acid (GABA)-A receptor. We investigated the method by which suvorexant was introduced in insomnia patients... -
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- Satisfaction Survey on Antipsychotic Formulations by Schizophrenia Patients in Japan
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Hatano M, Takeuchi I, Yamashita K, Morita A, Tozawa K, Sakakibara T, Hajitsu G, Hanya M, Yamada S, Iwata N, Kamei H
- KMID: 2522958
- Clin Psychopharmacol Neurosci.
- 2021 Nov;19(4):610-617.
- doi: 10.9758/cpn.2021.19.4.610
Objective: To identify factors affecting adherence to medication, a subjective questionnaire survey was administered to schizophrenia patients regarding the prescribed antipsychotic formulations. Methods: We evaluated the patients’ satisfaction and dissatisfaction with... -
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- A Questionnaire-based Study of the Views of Schizophrenia Patients and Psychiatric Healthcare Professionals in Japan about the Side Effects of Clozapine
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Takeuchi I, Hanya M, Uno J, Amano Y, Fukai K, Fujita K, Kamei H
- KMID: 2348477
- Clin Psychopharmacol Neurosci.
- 2016 Aug;14(3):286-294.
- doi: 10.9758/cpn.2016.14.3.286
OBJECTIVE: It is well documented that clozapine treatment causes agranulocytosis, but it can also induce drowsiness, constipation, and hypersalivation; however, these symptoms are usually less severe. It has been reported... -
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- Assessment of the Latent Adverse Events of Antipsychotic Treatment Using a Subjective Questionnaire in Japanese Patients with Schizophrenia
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Hatano M, Kamei H, Kato A, Takeuchi I, Hanya M, Uno J, Yamada S, Fujita K, Iwata N
- KMID: 2378481
- Clin Psychopharmacol Neurosci.
- 2017 May;15(2):132-137.
- doi: 10.9758/cpn.2017.15.2.132
OBJECTIVE: The adverse effects of antipsychotic agents can have a marked influence on medication adherence. In this study, we investigated the adverse events of antipsychotics that are less likely to... -
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