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The Role of Heat Shock Response in Insulin Resistance and Diabetes

Kondo T, Motoshima , Igata M, Kawashima , Matsumura , Kai H, Araki E

The expansion of life-style related diseases, such as metabolic syndrome (MS) and type 2 diabetes mellitus (T2DM), appears to be unstoppable. It is also difficult to cease their complications in...
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Genetic background, recent advances in molecular biology, and development of novel therapy in Alport syndrome

Nozu K, Takaoka Y, Kai H, Takasato M, Yabuuchi K, Yamamura T, Horinouchi T, Sakakibara N, Ninchoji T, Nagano C, Iijima K

Alport syndrome (AS) is a progressive inherited kidney disease characterized by hearing loss and ocular abnormalities. There are three forms of AS depending on inheritance mode: X-linked Alport syndrome (XLAS), autosomal...
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