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Rac-mediated actin remodeling and myosin II are involved in KATP channel trafficking in pancreatic beta-cells

Han YE, Lim A, Park SH, Chang S, Lee SH, Ho WK

AMP-activated protein kinase (AMPK) is a metabolic sensor activated during metabolic stress and it regulates various enzymes and cellular processes to maintain metabolic homeostasis. We previously reported that activation of...
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Polyphenol (-)-Epigallocatechin Gallate during Ischemia Limits Infarct Size Via Mitochondrial K(ATP) Channel Activation in Isolated Rat Hearts

Song DK, Jang Y, Kim JH, Chun KJ, Lee D, Xu Z

Polyphenol (-)-epigallocatechin gallate (EGCG), the most abundant catechin of green tea, appears to attenuate myocardial ischemia/reperfusion injury. We investigated the involvement of ATP-sensitive potassium (K(ATP)) channels in EGCG-induced cardioprotection. Isolated...
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