- Mismatch repair deficiency and clinicopathological characteristics in endometrial carcinoma: a systematic review and meta-analysis
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Jumaah AS, Al-Haddad HS, Salem MM, McAllister KA, Yasseen AA
- KMID: 2515925
- J Pathol Transl Med.
- 2021 May;55(3):202-211.
- doi: 10.4132/jptm.2021.02.19
Background: Loss of mismatch repair (MMR) occurs frequently in endometrial carcinoma (EC) and is an important prognostic marker. However, the frequency of MMR deficiency (D-MMR) in EC remains inconclusive. This... -
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- The frequency of POLE-mutation in endometrial carcinoma and prognostic implications: a systemic review and meta-analysis
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Jumaah AS, Salim MM, Al-Haddad HS, McAllister KA, Yasseen AA
- KMID: 2509500
- J Pathol Transl Med.
- 2020 Nov;54(6):471-479.
- doi: 10.4132/jptm.2020.07.23
Background: Endometrial carcinoma (EC) is classified into four distinct molecular subgroups including ultramutated DNA polymerase epsilon (POLE). POLE-mutated tumors have the best prognosis and are a promising target for immunotherapy.... -
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