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What’s new in breast pathology 2022: WHO 5th edition and biomarker updates

Muller K, Jorns JM, Tozbikian G

The 5th edition WHO Classification of Breast Tumours (2019) has introduced changes to our practices. Highlights are presented below, with a focus on modifications to morphological subtype categorization. In addition,...
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Vascular Ehlers-Danlos syndrome with distinct histopathologic features

Hwang HS, Song JW, Jang SJ

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Neuropathologic features of central nervous system hemangioblastoma

Yoda RA, Cimino PJ

Hemangioblastoma is a benign, highly vascularized neoplasm of the central nervous system (CNS). This tumor is associated with loss of function of the VHL gene and demonstrates frequent occurrence in...
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Juxtacortical chondromyxoid fibroma in the small bones: two cases with unusual location and a literature review

Oh SJ, Chung SH

Chondromyxoid fibroma is a rare bone tumor of cartilaginous origin, representing less than 1% of all bone tumors. It preferentially arises in the eccentric location of the metaphysis of a...
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A sinonasal yolk sac tumor in an adult

Shin J, Kim JH, Jung KC, Cho KJ

Yolk sac tumors (YSTs), which are also called endodermal sinus tumors, are malignant tumors of germ cell origin. These tumors usually occur in the gonads, but 20% of cases have...
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Adrenal hemangioblastoma

Koo JY, Lee KH, Choi JH, Chung HS, Choi C

Hemangioblastoma (HB) is a rare benign tumor that most commonly occurs in the cerebellum. HB is composed of neoplastic stromal cells and abundant small vessels. However, the exact origin of...
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Prognostic and clinicopathological significance of Fusobacterium nucleatum in colorectal cancer: a systemic review and meta-analysis

Kim Y, Cho NY, Kang GH

Background: Fusobacterium nucleatum has been identified to promote tumor progression in colorectal cancer (CRC). However, association between F. nucleatum and prognostic or clinicopathological features has been diverse among studies, which...
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Expression of prostate-specific membrane antigen in the neovasculature of primary tumors and lymph node metastasis of laryngeal squamous cell carcinomas

Erkılınç G, Yasan H, Kumbul YÇ, Sivrice ME, Durgun M

Background: Prostate-specific membrane antigen (PSMA) expression is encountered in tumor-associated neovascularization. Methods: PSMA-antibody was applied to the paraffin blocks of 51 patients who were diagnosed with squamous cell carcinoma of the...
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Frequency of PIK3CA mutations in different subsites of head and neck squamous cell carcinoma in southern Thailand

Dechaphunkul A, Thongwatchara P, Thongsuksai P, Dechaphunkul T, Geater SL

Background: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mutations have been reported in many cancers, including head and neck squamous cell carcinoma (HNSCC). The frequency of these mutations varies among tumor...
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